A Review Of The Effect Of S-Fluorouracil On The Outcome Of Trabeculectomy In Ibadan

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ABSTRACT


SUMMARY

Aim: In .ctrospectivclv assess the outcome of

trabecu lectcmv performed using an intraoperative

sponge soaked 5-fluorouracil (50 mg/ ml).

Methods: Trabeculcctornv with an intraoperative

sponge soaked with 5-f1uorouracil (5-fU) was

performed in 21 eyes of 1-+ patients. The reduction in

in traocular press ure (lOP), com plications and va ria tions

in visual acuity were noted.

Results: The mean preoperative lOP was 31.5 ± 10.6

mmHg. The mean postoperative lOP was 7.3 ±

5.7mmI-lg on the second postoperative day and 17.5 ±

9.SmmI-lg at 3 months. Postoperative complications

\ ere mostlv transient, vvith 330

0 of eyes requiring

postoperative c111tig!c1l1coma therapv to reduce lOP.

Visua l c1cuity Improved postopcr.itivclv in 3 eyes,

\'CHSCllL'din 9 cyes and remained the S,1l11l' In 9 eyes,

Conclusion: l.vcn though ,1 sm.ifl study, an

intraoperative sponge soaked vvil h 5-I:U seems to be a

safe and effective adjunct to tr.ibccu lcctomy.

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