Assessment Of Haemodynamic Changes Of Intrarenal Arteries In Sudanese Diabetic Patients

Abstract

Diabetes is worldwide in distribution and the incidence of both types

of primary diabetes is rising due to genetic and environmental

factors. Diabetes may cause life- threatening metabolic

complications associated with permanent and irreversible functional

and structural cells changes. Diagnostic ultrasound has become one

of the most important investigations used in the assessment of

vascular disease as it provides accurate information on the flow of

blood in the arteries and veins. This study aimed to evaluate

hemodynamic changes of the intra-renal arteries resistivity indices

(RI) related to diabetes mellitus (DM) using 2D B-mode and Doppler

ultrasonography. This study was carried out at diabetic referring

clinics of Omdurman teaching Hospital for 100 patients with known

diabetes with and without hypertension as sample and 50 normal

individuals as controls. The females were 64 representing64% and

males were 36 representing 36%, their ages ranged between 34-65

years and the disease duration was in the range of 1-30 years.

Controls were18 males representing 36% and 32females

representing 64%, their ages ranged between 39-71 years. All

patients and controls were underwent ultrasonography assessment

of renal size, cortical echogenicity and the intra-renal arteries

resistive index(RI) for upper, middle and lower poles and their

clinical history were registered. The body mass index (BMI) and

diabetic duration were assessed. The study results showed that

there were changes in the renal size and cortical echogenicity .The

Intra-renal arterial resistive index (RI) of the Sudanese diabetic

patients was higher than that of the controls and this increment was

statistically significant. The increment of Intra-renal arterial resistive

index (RI) of diabetics is positively correlated with age and duration

of disease. The (BMI) was inversely related to the intra-renal arterial

(RI). There was insignificant difference in intra-renal arterial (RI)

between hypertensive diabetics and non-hypertensive diabetics.

Sudanese females are more affected by diabetes than Sudanese males.