Assessment Of Thera Tional Use Of Selected Antffiacterials Drugs (Amoxicillin, Cotrimoxazole And Metronidazole) In Kampala International University Teaching And Kitagata Hospitals.

ABSTRACT

Backgrmmd:

More than 50% of all medicines are irrationally used in the world. Rational use of medicines

(RUM) means that the right patient receives the right drug, in the right dose, for the right

duration, and at the lowest cost for him/her and the community. In a nutshell treatment must

follow the standard treatment guidelines of that area. In this case Uganda, the Uganda Clinical

Guidelines for treatment of Common Infections is used. The problem of rational use is even

most dire with antibacterial drugs, especially commonly used ones where resistance is ever

grow mg.

Purpose of study:

To assess whether amoxicillin, cotrimoxazole and metronidazole are rationally used in KlUTH

and Kitagata hospital

Methods:

Prescriptions from each hospital containing the above antimicrobial therapy were analysed to

find fi·equency of adherence to STGs by prescribers as a measure of rational use. Other

indictors of rational use such as generic name use and definitive diagnosis such as laboratory

testing were measured. Questionnaires were used to assess knowledge and frequency of use of

STGs.

Results:

From KlU-TH 7£.4•% of prescription were in accordance with STGs, KITAGATA recorded

57.1% of these drugs were prescribed in accordance with STGs. 9.£% of respondents from KIU

used Laboratory diagnosis always, from Kitagata only £% reported this.

Conclusions:

IUU-TH had higher rates of rational use of antibiotics compared to Kitagata hospital.

Cotrimoxazole had the highest rates of rational use. STGs play an important role in promoting

rational use of antibacterials.

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