Association Between Natural Cytotoxicity Triggering Receptor- 3 Polymorphisms (-172a/G And -412c/G) And Interferon-Gamma Levels In Children Aged 3-36 Months With Severe Plasmodium Falciparum

ABSTRACT

In sub-Saharan Africa, Plasmodium falciparum infection is a major cause of morbidity and mortality mostly among children under five years. In Kenya, severe malaria anaemia prevalence is at 19%. In malaria holo-endemic region of western Kenya, P. falciparum infections account for major proportion of children with anaemia that leads to severe malaria anaemia (SMA, Hb