Dietary Consumption of Virgin Coconut Oil Ameliorates Lipid Profiles in Diabetic Rats

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Virgin coconut oil (VCO) is a saturated fat with promising antidiabetic properties but its ameliorative effect on lipid profiles
in diabetics is rarely reported. Therefore, in this study, a total of fifteen (15) male rats weighing 200–250 g were divided into 3
experimental groups (𝑛 = 5).Group I (control) andGroup II (diabetic control group) were fed a normal rat chowwhile Group III
(diabetic test group) was fed a 10% VCO diet for 3 weeks. Group II and Group III were made diabetic by intraperitoneal injection
of 150mg/kg of alloxan. After 72 hours of injection, blood glucose was tested to confirm diabetes mellitus. After 3 weeks, the
animals were sacrificed to collect blood samples for lipid profile analysis.Theresults showed a significant increase in concentrations
of triglyceride, total cholesterol, low density lipoprotein, and very low density lipoprotein and decrease in concentration of high
density lipoprotein in Group II when compared to Group I. Also, the concentrations of triglyceride, total cholesterol, low density
lipoprotein, and very low density lipoprotein except high density lipoprotein significantly reduced in Group III when compared to
Group II (𝑃 < 0.01, 0.001). VCO consumption can be claimed to ameliorate lipid levels in diabetes mellitus.

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Dietary Consumption of Virgin Coconut Oil Ameliorates Lipid Profiles in Diabetic Rats

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