Estimation of Prothrombin Time, Activated Partial Thromboplastin Time and platelets count in Diabetes Type II patients in Khartoum State

Abstract

This is an analytical case control study, conducted during the period from

July to November in Best Care Hospital. The study aimed to evaluate

prothrombin time, international normalized ratio (INR), activated partial

thromboplastin time and platelets count among patients with diabetes

type II. Thirty samples were collected from 12 males and 18 females their

age range between 30—80 and a means of 51 years, and diabetic duration

from 1—30 years. The patients were divided into diabetic controlling and

un-controlling groups in respect to level of HbA1C (less than 8%, more

than 8%) respectively.

Thirty control samples were collected from healthy non diabetic

volunteers with same age ranges. All subjects were questionnaired during

blood collection about some clinical information. Blood samples and

controls were investigated for PT, INR, APTT and Platelets count using

coagulometer and sysmex semi-automated, hematology analyzer

respectively. There was no significant difference in PT, INR, APTT and

platelets count in diabetic patients compare with control group (P-value

0.893, 0.971,0.321 and 0.703) respectively. The results obtained show that diabetic patients have normal coagulation mechanisms.

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