Medical & Health Sciences

Browse Medical & Health Sciences Topics/Papers by subfields

Research Papers/Topics Medical & Health Sciences

What is the clinical merit of bioactive glass in restorative dentistry? [November 28, 2017]

Search result: One systematic review was found. Clinical outcomes: The limited results suggest that bioactive glass may be effective in remineralising dentin. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity of results and thus do not replace...

What are the clinical merits of CAD/CAM manufactured dentures? [November 27, 2017]

Search result: Two older systematic reviews (until June 2012) and one recent clinical trial (2016) were found. Clinical outcomes: The results suggest that CAD/CAM post-sintered denture frameworks are superior to CAM pre-sintered denture frameworks and that CAD/CAM systems may show less marginal discrepancy than conventional methods for framework fabrication.. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and ...

How do Composite (CAD/CAM) crowns compare to ceramic crowns in terms of clinical restoration survival? [November 26, 2017]

Search result: One clinical trial was found. Clinical outcomes: The results suggest that Composite (CAD/CAM) crowns are inferior to ceramic crowns after 3 years. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity of results and thus do not repl...

How do Fibre posts compare to Metal posts in terms of clinical restoration survival? [November 25, 2017]

Search result: Two systematic reviews and two additional trial reports that were not covered by the systematic reviews were found. Clinical outcomes: The older systematic review (2005) included only one relevant trial not included in the other more recent systematic review (2014) and stated higher failure risk for metal-posts. However, the more recent systematic review included 14 trials and found no significant differences. In addition, one trial indicated higher fracture risk and lower ...

How do 2-step etching systems compare to 3-step etching systems in terms of clinical restoration survival? [November 20, 2017]

Search result: Two systematic reviews and one additional trial reports were found. Clinical outcomes: While the trial report and one systematic review indicated no significant difference, one other systematic review suggests 3-step systems to be superior to 2-step systems for composite restorations in cervical cavities and inferior for composite restorations in load-bearing cavities of permanent teeth. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic system...

How do 1-step etching systems compare to 3-step etching systems in terms of clinical restoration survival? [November 18, 2017]

Search result: Two systematic reviews and one additional trial report were found. Clinical outcomes: While the trial report indicated no significant difference, one systematic review provided no data while the other indicated that 3-step self-etching systems to be superior to 1-step self-etching systems (no information were provided for 3-step versus 1-step etch-and-rinse systems). [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the ...

How do 1-step etching systems compare to 2-step etching systems in terms of clinical restoration survival? [November 17, 2017]

Search result: Two systematic reviews and 5 additional trial reports were found. Clinical outcomes: While the trial reports indicate no significant difference, the systematic reviews suggest 2-step systems to be superior to 1-step systems. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as th...

How do HEMA free bonding agents compare to HEMA containing bonding agents in terms of clinical restoration survival? [November 16, 2017]

Search result: Three studies were found. Clinical outcomes: The result indicates no differences between HEMA containing and HEMA-free bonding agents for most clinical outcomes after 3 and 5 years. In addition, restorations with HEMA-free agents appear to have some higher dentin retention after 5 years, while exhibiting more incisal marginal defects and discolorations after 3 years. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the ...

Clinical effect of MTA cement for pulp capping [November 14, 2017]

Search result: 2 systematic reviews and 9 clinical trials were found. Clinical outcomes: The results suggest MTA to be effective for pulp capping. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity of results and thus do not replace the need fo...

Clinical merits of restorative treatment of root (cervical) caries lesions [November 13, 2017]

Search result: 7 trials were found. Clinical outcomes: The results suggest that various composites (nanohybrid, flowable) show good results. Etch-and-rinse adhesives appear to be superior to all-in-one adhesives, while compomers and resin-modified glass-ionomers appear to be less effective than composites. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidenc...

What is the Clinical Longevity of Lithium Disilicate Ceramics?

Search result: 5 trials and 6 systematic reviews were found. . Clinical outcomes: The results suggest that: (i) for lithium disilicate single crowns, the existing evidence indicates excellent short-term survival rates, but the evidence for medium-term survival is limited; (ii) for lithium disilicate fixed dental prostheses, the evidence for short-term survival is fair, although limited, but the evidence for medium-term survival is not promising; (iii) there is contradicting evidence whether...

Have stannous ions any remineralising effect on dental tissues? (Therapeutic) [November 11, 2017]

Search result: 11 trials were found. Clinical outcomes: The results suggest that stannous ions may have a caries/demineralisation preventive effect (particularly when stannous fluoride was compared to sodium fluoride). [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of preci...

Have stannous ions any remineralising effect on dental tissues? (Therapeutic) [November 10, 2017]

Search result: 5 trials were found. Clinical outcomes: The results of the laboratory trials appear contradictory particularly when stannous fluoride was compared to sodium fluoride). [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity of result...

Have stannous ions any antibiotic effect on oral bacteria? [November 9, 2017]

Search result: 9 trials were found. Clinical outcomes: The results of the mainly laboratory trials suggest that stannous ions have an inhibiting effect on oral bacteria (particularly when stannous fluoride was compared to sodium fluoride). [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as th...

Has zinc any antibiotic effect on oral bacteria? [November 8, 2017]

Search result: 13 trials were found. Clinical outcomes: The results of the mainly laboratory trials suggest that zinc has an inhibiting effect on oral bacteria. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity of results and thus do not repla...


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