Medical & Health Sciences

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Research Papers/Topics Medical & Health Sciences

Prion and Prion Disease: Immunobiology, Pathogenesis and Potential Threat to Mankind

ABSTRACT Prion diseases, also known as Transmissible Spongiform Encephalopathies (TSEs), are fatal neurodegenerative disorders with characteristic sponge-like microscopic appearance in the infected brain. They are caused by a protein-only particle consisting of an abnormal isoform (PrPSc) of the normal ubiquitous cellular prion protein PrPc. Prion diseases affect both human and animals, and can cause interspecies transmission. In humans, there are six different phonotypes of prion diseases, i...

EFFECT OF AQEUOUS EXTRACT OF Rauwola vomitoria ROOT EXTRACT ON ISOLATED RABBIT INTESTINE

Rauwolfia vomitoria is a natural medicinal herb which has been used over the years for the treatment of hypertension and mental disorders. This is to investigate the inhibitory effect of RAUWOLFIA VOMITORIA aqueous root extract on invitro isolated rabbit intestine precontracted with Acetylcholine. The effect of the root extract was compared with adrenaline.seven healthy adult rabbit bred in the animal house of college of basic medical science delta state university,abrake were alowed to aclim...

Toxicity Assessment of Stem Bark Extracts

Spondias mombin is depends on for various herbal remedies for the treatment of numerous health conditions. This study is to evaluate the In-vivo toxic effect of Stem bark extracts of Spondias mombin on in male and female albino rats. In-vivo  toxicity test was carried out with modified Lorke’s method. Forty two (42) male and female albino rats weighing between 120-180g were used for the sub-chronic study. The rats were divided into five groups A- D (n=12). The albino rats were divided ...

Effect of Lead (Pb) on the Growth and Development of Two Varieties of Vigna Unguiculata (Cowpea) in Jere Local Government Area, Borno State, Nigeria

PROPOSED TOPIC:                                         Effect of Lead (Pb) on the growth and development of two varieties of vigna unguiculata (cowpea) in Jere Local Government Area Borno State, Nigeria     NAME                                                           Emmanuel Bwala THLAMA     REGISTRATION NUMBER:                        PGA/13/09/02/07777       DEGR...

Endocrine and Neuroendocrine Factors Regulating Testicular Functions

The spermatogenic and steroidogenic functions of the testes is finely regulated by the brain (on stimulation), the master endocrine gland, and local factors produced by the testes. During intrauterine life the proliferation of primitive germ cells and the formation of the testes is carefully directed by testosterone, secreted by leydig cell on activation by human chorionic gonadotropin (HCG) released by the placenta. After birth, hormonal regulation of testes stop and the testes remain quicen...

Dangers of Dumping Waste Into Public Drains

Introduction Background of the study Statement of the problem Objective of the problem Research question Definition of term Literature reviews Data analysis Recommendation References

Knowledge and perception of vasectomy among male staffs of Novena University Ogume Delta State Nigeria

Background: Vasectomy is a simple effective and safe surgical procedure for permanent male fertility control. However, high acceptance rates of vasectomy have been reported in developed countries, while low acceptance rates have been reported in developing countries like Nigeria.  Objective: This study was designed to investigate the knowledge and perception of vasectomy among male staffs of Novena University Ogume, Delta State Nigeria. Methods: A cross-sectional study was conducted among 1...

Knowledge and Use of Antiretroviral Drugs in Prevention of Mother to Child Transmission of HIV/AIDS Amongst HIV Infected And Uninfected Patients in Okwe General Hospital, Asaba: A Case-Contro

Background: Perinatal transmission of HIV/AIDS also known as Mother to Child Transmission of HIV/AIDS is the most prevalent source of pediatric HIV infection.  Objective: Therefore, this case-control study was designed to investigate the knowledge and use of antiretroviral drugs in prevention of mother to child transmission of HIV/AIDS amongst HIV infected and uninfected patients.  Settings: The study was carried out in Okwe General Hospital in Asaba.  Methods: A case-control study was co...

AWARENESS AND KNOWLEDGE OF AUTISM SPECTRUM DISORDERS AMONG MOTHERS IN UKWUANI LOCAL GOVERNMENT AREA, DELTA STATE

Autism Spectrum Disorders (ASD) is defined as a group of neurodevelopment disorders that are usually diagnosed in early childhood. A cross-sectional study was conducted among 192 women of reproductive age selected from three communities of Ukwuani Local Government Area. A semistructured questionnaire was administered to obtain information from respondents. Mean age of respondents was 57.9 ± 9.8 years, and 105 (54.70%) were married. More than half 108 (56.30%) of the respondents were aware of...

ASSESSING THE PREFERENCE OF ORTHODOX AND TRADITIONAL MEDICINE IN MALARIA TREATMENT AMONG ENERHEN COMMUNITY MEMBERS, DELTA STATE, NIGERIA

This study assessed the preference of orthodox and traditional medicine in malaria treatment among community members in Enerhen, Delta-state Nigeria. A cross-sectional study design was adopted for the study to assess 375 participants selected through systematic sampling in Enerhen community. Data was collected through a semi-structured questionnaire and was analyzed for descriptive statistics, chi-square and ANOVA test at p

KNOWLEDGE, ATTITUDE AND USE OF NON-PRESCRIPTION DRUGS AMONG PREGNANT WOMEN IN OKWE GENERAL HOSPITAL ASABA DELTA STATE, NIGERIA

Aim: The study was aimed at assessing the knowledge, attitude and use of non-prescription drug among pregnant women in Okwe General Hospital Asaba in Delta State. Study Design: The study was a descriptive cross sectional survey. Place and Duration of Study: Okwe General Hospital Asaba in Delta State, Nigeria. The study was conducted between June to July 2015 Methodology: A semi-structured questionnaire was used and administered to 103 randomly selected pregnant women at Okwe General Hospital ...

KNOWLEDGE OF PUBERTY, SEXUALLY TRANSMITTED INFECTIONS AND SEXUAL BEHAVIOUR AMONG VERY YOUNG MALE ADOLESCENT STUDENTS’ IN SOUTH-SOUTH, NIGERIA

Aim: There is impassable knowledge on the transition between childhood and adulthood among adolescents. This study was designed to investigate the knowledge of puberty, sexually transmitted infections and sexual behaviour among very young male adolescent students in South-South, Nigeria. Study Design: A descriptive cross-sectional study was used. Place and Duration of Study: Agbor Metropolis in Delta State, Nigeria, between February to April 2015. Methodology: The study utilized both quantita...

Prevalence of neonatal jaundice in Eku Baptist Community Hospital in Delta State Nigeria

ABSTRACT The prevalence of neonatal jaundice among newborn babies in Eku Baptist Community Hospital in Delta State was studied between January 2007 and May 2013. A total of 2,509 neonatal case folders were reviewed to determine the prevalence, pattern of occurrence, and associated risk factors of neonatal jaundice among the newborn babies aged between 1 and 28 days. Neonatal jaundice accounted for a total prevalence of 52. 6 in 1000 of the total number of cases reviewed.  There was significa...

Prevalence of Physical Hazards in Public Primary Schools in South-West Nigeria

Abstract: Aim: Physical hazards (PHs) in the school environment compromise health of primary school children worldwide. Thus the study investigated the prevalence of physical hazards in public primary schools in South-West Nigeria. Methods: The study was a cross-sectional survey that involved the selection of 456 teachers from 30 selected Public Primary Schools using a 4-stage random sampling technique. Data were collected through an observational checklist and a semi-structured questionnai...


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