Medical & Health Sciences

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Research Papers/Topics Medical & Health Sciences

Anti-predator Crèches and Aggregations of Ant-mimicking Jumping Spiders (Araneae: Salticidae)

Abstract: Myrmarachne assimilis, an ant-like jumping spider (Araneae, Salticidae) from the Philippines and a Batesian mimic of Oecophylla smaragdina, the Asian weaver ant, aggregates on leaves in the company of its model. All stages in this species’ lifecycle are sometimes found in nest complexes (nests connected to each other by silk). Although aggregating and forming nest complexes is known for a few other salticid species, the aggregations of M. assimilis have some unusual haracteristic...

A Randomized Trial to Monitor the Efficacy and Effectiveness by QT-NASBA of Artemether-lumefantrine versus Dihydroartemisinin-piperaquine for Treatment and Transmission Control of Uncomplicat

Abstract: Background: Many countries have implemented artemisinin-based combination therapy (ACT) for the first-line treatment of malaria. Although many studies have been performed on efficacy and tolerability of the combination arthemeter-lumefantrine (AL) or dihydroartemisinin-piperaquine (DP), less is known of the effect of these drugs on gametocyte development, which is an important issue in malaria control. Methods and results: In this two-arm randomized controlled trial, 146 children ...

Distribution of Mosquito Larvae Within the Paddy and its Implication in Larvicidal Application in Mwea Rice Irrigation Scheme, Central Kenya

Abstract: Distribution of mosquito larvae in inundated rice fields is poorly known despite its profound implications in implementation of vector control programs. Based on oviposition behavior of gravid females and biotic and abiotic conditions of the rice field, distribution of mosquito larvae within the paddy may vary greatly. As a guide to implementation of mosquito vector control program targeting the aquatic stages in the rice fields in Mwea, studies were conducted to determine the dist...

Hydrological modeling of geophysical parameters of arboviral and protozoan disease vectors in Internally Displaced People camps in Gulu, Uganda

Abstract: Background: The aim of this study was to determine if remotely sensed data and Digital Elevation Model (DEM) can test relationships between Culex quinquefasciatus and Anopheles gambiae s.l. larval habitats and environmental parameters within Internally Displaced People (IDP) campgrounds in Gulu, Uganda. A total of 65 georeferenced aquatic habitats in various IDP camps were studied to compare the larval abundance of Cx. quinquefasciatus and An. gambiae s.l. The aquatic habitat datas...

Host Choice and Multiple Blood Feeding Behaviour of Malaria Vectors and Other Anophelines in Mwea Scheme, Kenya

Abstract: Background: Studies were conducted between April 2004 and February 2006 to determine the bloodfeeding pattern of Anopheles mosquitoes in Mwea Kenya. Methods: Samples were collected indoors by pyrethrum spay catch and outdoors by Centers for Disease Control light traps and processed for blood meal analysis by an Enzyme-linked Immunosorbent Assay. Results: A total of 3,333 blood-fed Anopheles mosquitoes representing four Anopheles species were collected and 2,796 of the samples were ...

Blood-Feeding Patterns of Culex Quinquefasciatus and other Culicines and Implications for Disease Transmission in Mwea Rice Scheme, Kenya

Abstract: Studies were conducted in Mwea Rice Scheme, Kenya during the period April 2005 and January 2007 to determine the host-feeding pattern of culicine mosquitoes. Mosquitoes were collected indoors and outdoors and tested for human, bovine, goat, and donkey blood meals by an Enzyme-Linked Immunosorbent Assay. A total of 1,714 blood-engorged samples comprising Culex quinquefasciatus Say (96.1%), Culex annulioris Theobald (1.8%), Culex poicilipes Theobald (0.9%), Aedes cuminsi Theobald (1....

Comparison of Mosquito Control Programs in Seven Urban Sites in Africa, the Middle East, and the Americas

Abstract: Mosquito control programs at seven urban sites in Kenya, Egypt, Israel, Costa Rica, and Trinidad are described and compared. Site-specific urban and disease characteristics, organizational diagrams, and strengths, weaknesses, obstacles and threats (SWOT) analysis tools are used to provide a descriptive assessment of each mosquito control program, and provide a comparison of the factors affecting mosquito abatement. The information for SWOT analysis is collected from surveys, focus...

The Association Between Distance to Water Pipes and Water Bodies Positive for Anopheline Mosquitoes (Diptera: Culicidae) in the Urban Community of Malindi, Kenya

Abstract: The increasing risk of mosquito-borne diseases in African urban environments has been partly attributed to failed planning and resource underdevelopment. Though engineered systems may reduce mosquito proliferation, there are few studies describing this relationship. This study investigates how engineered systems such as roads and piped water systems affect the odds of anopheline immatures (i.e., larvae and pupae) occurring in water bodies located in Malindi, Kenya. Anopheles gambia...

Screening Mosquito House Entry Points as a Potential Method for Integrated Control of Endophagic Filariasis, Arbovirus and Malaria Vectors

Abstract: Background: Partial mosquito-proofing of houses with screens and ceilings has the potential to reduce indoor densities of malaria mosquitoes. We wish to measure whether it will also reduce indoor densities of vectors of neglected tropical diseases.Methodology: The main house entry points preferred by anopheline and culicine vectors were determined through controlled experiments using specially designed experimental huts and village houses in Lupiro village, southern Tanzania. The b...

Serological evidence of Flavivirus circulation in human populations in Northern Kenya: an assessment of disease risk 2016–2017

Abstract: Background: Yellow fever, Dengue, West Nile and Zika viruses are re-emerging mosquito-borne Flaviviruses of public health concern. However, the extent of human exposure to these viruses and associated disease burden in Kenya and Africa at large remains unknown. We assessed the seroprevalence of Yellow fever and other Flaviviruses in human populations in West Pokot and Turkana Counties of Kenya. These areas border Uganda, South Sudan and Ethiopia where recent outbreaks of Yellow fev...

Enhancing vector refractoriness to trypanosome infection: achievements, challenges and perspectives.

Abstract: With the absence of effective prophylactic vaccines and drugs against African trypanosomosis, control of this group of zoonotic neglected tropical diseases depends the control of the tsetse fly vector. When applied in an area-wide insect pest management approach, the sterile insect technique (SIT) is effective in eliminating single tsetse species from isolated populations. The need to enhance the effectiveness of SIT led to the concept of investigating tsetsetrypanosome interaction...

Strengthening community and stakeholder participation in the implementation of integrated vector management for malaria control in western Kenya: a case study

Abstract: Integrated vector management (IVM) is defined as a rational decision-making process for the optimal use of resources for vector control. The IVM approach is based on the premise that effective control of vectors and the diseases they transmit is not the sole preserve of the health sector. It requires the collaboration and participation of communities and other stakeholders in public and private sectors. Community participation is key to the success of IVM implementation at the loca...

Effects of phytochemicals on predatory decision making in a spider

Abstract: Animals with small nervous systems may be prone to limitations in processing ability when confrontedwith a diversity of stimuli, especially if these involve multiple sensory modalities. We investigated theeffect of the odour of the plantLantana camaraand its dominant volatile compound,b-caryophyllene, onthe prey choice decisions ofEvarcha culicivora,a jumping spider (Salticidae) that frequently visitsL. camaraas a site to mate and to obtain nectar.Evarcha culicivoraexpresses a stro...

Evolutionary genomics at the human-environment interface in Africa.

Abstract: We report on the first meeting of SMBE in Africa. SMBE Malawi was initiated to bring together African and international researchers who use genetics or genomics to study natural systems impacted by human activities. The goals of this conference were 1) to reach a world-class standard of science with a large number of contributions from Africa, 2) to initiate exchange between African and international researchers, and 3) to identify challenges and opportunities for evolutionary geno...

Long lasting insecticidal mosquito nets (LLINs) ownership, use and coverage following mass distribution campaign in Lake Victoria basin, Western Kenya

Abstract: Background: Long-lasting insecticidal nets (LLINs) are the most widely used malaria prevention and control intervention in Africa. However, their effectiveness may vary depending on their local geographic coverage, ownership and use at household level. This study aimed at assessing LLINs ownership and use following mass distribution campaign in western Kenya. Methods: A cross-sectional study was conducted in November 2017. A total of 160 households were randomly selected from 16 vi...


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