Search result: One article, reporting on 2 clinical trials, was identified, concerning plaque pH-decrease after sucrose challenge: (a) comparison of CPP-ACP containing paste with no paste; (b) comparison of CPP-ACP containing paste with placebo. Clinical outcomes: The results show a significant reduction in plaque pH fall after sucrose challenge with CPP-ACP containing paste State of evidence and recommendations: The results of both reported trials need to be regarded with caution due to...
Search result: No clinical trials or 2-arm (controlled) trials of any design (in-situ, in-vitro) could be found. Only one single-arm/longitudinal in-situ trial was identified. This trial used the test subjects as control group (without CPP-ACP). Clinical outcomes: The results of this trial showed an increase of the saliva pH in 16 out of 25 subjects after 3 weeks. A change from the initial level of pH 6.6 to the final level of around pH 7.6 was observed. State of evidence and recommendation...
Search result: Ten clinical trials were found and traced concerning high-viscosity conventional GIC. No trials were identified comparing strontium or calcium low-viscosity conventional GIC. All identified trials compared Fuji IX for strontium and Ketac Molar for calcium based GIC. Clinical outcomes: The overall results suggest no difference between Fuji IX and Ketac Molar in the clinical outcomes of: recurrent caries, occlusal wear and colour match. Two of the 10 trials suggest a higher fa...
Search result: Three clinical trials with a laboratory component were found. Clinical outcomes: There appears to be no difference in the pulp response between conventional glass-ionomer cement (C-GIC) and CaOH-cement (CaOH is considered to be the gold standard in pulp treatment due to its high tissue supporting properties. Lack of difference between C-GIC and CaOH suggest high bio-compatibility of C-GIC concerning pulp tissue). State of evidence and recommendations: The current level of c...
Search result: One clinical trial was found. Clinical outcomes: There appears to be no difference in the success rate of both types. State of evidence and recommendations: The current level of clinical evidence to this topic appears to some extent contradictory and may still be limited in quantity and quality. Thus more trials are needed in order to confirm the current results. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the den...
Search result: Five clinical trials were found. Clinical outcomes: There appears to be no difference in the survival rate of both types of restorations. Post-operative sensitivity appears to be reduced for a short-time period after restoration placement when a GIC liner is used. State of evidence and recommendations: The current level of clinical evidence to this topic appears to some extent contradictory and may still be limited in quantity and quality. Thus more trials are needed in orde...
Search result: Two clinical trials were found. Clinical outcomes: There appears to be no difference in the survival rate of both types of restorations after 2 years. State of evidence and recommendations: The current level of clinical evidence to this topic appears to some extent contradictory and may still be limited in quantity and quality. Thus more trials are needed in order to confirm the current results. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s period...
Search result: Four clinical trials were found. The limited number of clinical trials is surprising considering that the topic of GIC/Composite sandwich restorations was very popular 20 years ago. However, the bulk of research studies appeared to be limited to a very large number of laboratory (in-vitro) trials, only. Although important to clarify material characteristics, laboratory trials are unable to provide information how well these restorations really perform in the clinic, particu...
Search result: Three clinical trials were found. Clinical outcomes: The results indicate that additional selective enamel etching does not improve the clinical performance of restorations. State of evidence and recommendations: The current level of clinical evidence to this topic appears to some extent contradictory and may still be limited in quantity and quality. Thus more trials are needed in order to confirm the current results. [‘Preliminary Systematic Literature Searches’ are ba...
Search result: Eleven clinical trials were found. Clinical outcomes: Minor or no improvements are reported when selective enamel etching was used. Selective enamel etching may not pose a hazard in terms of postoperative hypersensitivity. State of evidence and recommendations: The current level of clinical evidence to this topic appears to some extent contradictive and may still be limited in quantity and quality. Thus more trials are needed in order to confirm the current results. [‘Prel...
Search result: Eight articles reporting on 4 clinical trials after different follow-up periods were found. Clinical outcomes: The results indicate no difference in retention and anatomic form of restorations after 1 – 3 years. Marginal adaptation appears to be superior for etch-and-rinse systems after 1 – 2 years and no difference was found after 3 years. Marginal discoloration is significantly more observed for (1-step) self-etch systems. Post-operative sensitivity was the same for bo...
Search result: Eight clinical studies were found. Clinical outcomes: The results suggest efficacy of resin-infiltration technique to stop caries progression and to improve aesthetic appearance of white spot lesions (WSL). However, discomfort levels appear to be higher than with other noninvasive interventions. State of evidence and recommendations: The quality of the existing evidence requires further assessment. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s peri...
Search result: 21 clinical studies were found. In-situ studies, as well as studies including ACP/casein materials not covered by the Recaldent technology were not included. Clinical outcomes: The results regarding the clinical efficacy of CPP-ACP in the prevention and treatment of dental caries, i.e. slowing the progress of early caries lesions/white spot lesions appears to be contradictive and no conclusive statement can yet be made based on the available evidence. State of evidence and r...
Search result: Only one clinical study was found. Clinical outcomes: The results indicate no difference in the caries preventive effect between both materials as fissure sealants in permanent teeth. The retention rate of RM-GIC in pits and fissures was higher than for conventional GIC. State of evidence and recommendations: The quality of the existing evidence requires further assessment. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches o...
Search result: Only two clinical studies were found. Clinical outcomes: The results indicate that GICs release more fluoride under clinical conditions than fluoride containing composite resin. State of evidence and recommendations: The quality of the existing evidence requires further assessment. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are l...