ABSTRACT BACKGROUND: Malaria rapid diagnostic tests (MRDTs) are important for malaria disease management. However, performance of the RDTs is affected when the targeted antigens in the parasite have a variation or are altogether absent. The most common parasite target antigen in RDTs, Plasmodium falciparum histidine-rich protein 2 (HRP2), has been reported to be absent in some P. falciparum parasites. Loss of the pfhrp2 in P. falciparum parasites affects the accuracy of PfHRP2 based RDT ...
ABSTRACT A cross sectional study was carried out among HIV positive patients attending St. Mary Catholic General Hospital, Eleta, Ibadan. All data obtained from subjects in the course of this study were strictly treated as confidential. One hundred and fifty (n = 150) serum samples were randomly collected from the people living with HIV who have given their informed consent. These samples was screened for hepatitis B serological markers (i.e. HBsAg, anti-HBs, HBeAg, HBeAb and anti-HBc) using...
ABSTRACT Prion diseases, also known as Transmissible Spongiform Encephalopathies (TSEs), are fatal neurodegenerative disorders with characteristic sponge-like microscopic appearance in the infected brain. They are caused by a protein-only particle consisting of an abnormal isoform (PrPSc) of the normal ubiquitous cellular prion protein PrPc. Prion diseases affect both human and animals, and can cause interspecies transmission. In humans, there are six different phonotypes of prion diseases, i...