ABSTRACT Trypanosomosis is one of the most devastating diseases of animals caused by infection with a protozoan parasite trypanosome, which is transmitted by tse-tse fly. Besides anaemia, which is a cardinal symptom of the disease, infection also impairs the immune system of animals and renders them more susceptible to other. Under natural field condition, in areas where trypanosome and helminth parasites are endemic, mixed infection appears to be common. A study was conducted to determine t...
Abstract This study evaluated the use of the methanolic leaf extract of Palisota hirsuta in postsurgical wound management using different wound models in rats. It also assessed the antibacterial activity of the plant extract as well as the possible toxic effects on the liver, kidney and blood. The yield of the methanolic leaf extract of Palisota hirsuta (PHLE) was 5.98 % w/w and it was dark green, pasty in consistency with a pungent smell. In the excision wound model, PHLE at 1% and 4 % sign...
ABSTRACT This work was designed to study the effects of Trypanosoma brucei and Trypanosoma congolense infection on the renal function of mongrel dogs. Also, the effects of treatment of the infection with diaminazene aceturate were evaluated. Sixteen (16) male mongrel dogs aged between 3 and 6 months, and weighing between 2.5 and 5.2 kg were used for the study. The dogs were acquired, numbered, tagged and weighed. The dogs were kept in clean metal cages in a fly proof house and were fed once ...
ABSTRACT This study was conducted to document the occurrence and characteristics of mycotic agents isolated from trade horses and donkeys in Obollo-Afor, Enugu State. A total of 497 horses and 65 donkeys presented for sale at Obollo-Afor horse/donkey market during the wet season (June to August 2014) and dry season (January to March 2015) were examined for skin lesions. For each horse/donkey examined, the location of skin lesion as well as the sex of the animal was recorded. Each skin lesion...
ABSTRACT The high turn-over rate and quest for white meat have given more impetus to poultry production. The need to increase production and meet the demand for poultry meat has necessitated the use of veterinary drugs, especially antimicrobials, for therapeutic, prophylactic and growth promotion purposes in poultry farming. These drugs tend to accumulate in tissues and organs as residues. The presence of drug residues in tissues above the maximum residue limit (MRL) becomes violative if wit...
ABSTRACT The methanolic root bark extract of Afzelia Africana was tested for antidiabetic activities in-vivo. The acute toxicity of the extract was tested in mice and the result showed that the extract 6 has low toxicity. Investigation on the phytochemical constituents of the plant extract revealed the presence of flavonoids, tannins, alkaloids, steroids and saponins. The plant extract was tested for antidiabetic activities in alloxan-induced diabetic mice at doses; 62.5 mg/kg, 125 mg/kg, 25...
ABSTRACT Effect of stabilizing chloroquine phosphate in a synthetic Aluminium Magnesium silicate (Nanoparticles) on the antiplasmodial activity of the drug was investigated. Mice infected with Plasmodium berghei were treated with chloroquine phosphate at 7 mg/kg, 5 mg/kg and 3 mg/kg dose levels respectively. Two subgroups at each dose level were treated with chloroquine phosphate alone and with a drug formulation of 20% chloroquine phosphate in the synthetic Aluminium Magnesium Silicate (AMS...
ABSTRACT Fifteen dogs of similar age (8-12 months) were used for the clinical study. They were randomized into 3 groups (CH1-5, CL1-5 AND AC1-5). Simple transverse femoral fractures were created under anaesthesia using a bone saw. Spatial alignment of the bone was achieved by insertion of an intramedullary pin. Radiographic assessment confirmed that the pins were intact and internal fixation was thorough. Celecoxib (Celebrex® Pfizer Inc, Germany) was supplied in encapsulated powdered form a...
ABSTRACT This study was carried out to evaluate the chemical composition and bacterial load of donkey meat as well as the prevalence of verotoxigenic Escherichia coli (VTEC). The study adopted the survey and experimental designs. A questionnaire, which comprised three sections, was developed to elicit information on the demographics, source of meat, and factors that influence choice of meat consumed by the respondents. The instrument for data collection was validated by three experts. A pilo...
ABSTRACT The contractile activity of M. pruriens and the relaxatory property of C. odorata was investigated using in vitro methods in the rat. M. pruriens caused a dose-dependent increase in uterine muscle contraction with a maximum peak in amplitude with 0.57 mg/ml of the extract and an EC50 of 2.7 mg/ml. The contraction was unaffected by atropine sulphate (0.042 µmol), but abolished by isoprenaline (0.06-0.23 µmol), salbutamol (0.012-0.4 µmol) and adrenaline (16 nmol).Uterine muscle con...
ABSTRACT Trypanosomosis is a vector-borne, tropical disease that causes mortality and morbidity in livestock and humans. In this study we investigated the risk factors for trypanosome infection in cattle in the Maasai Steppe of northern Tanzania. We assessed the influence of age, sex, herd size and history of treatment against trypanosomosis as risk factors of trypanosome infection. Cattle blood samples were collected from 150 cattle in three villages in the vicinity of Tarangire National P...
ABSTRACT Cryptosporidium is an intracellular zoonotic protozoan parasite that causes cryptosporidiosis, a diarrheal disease of humans and domestic animals. The parasite has been reported in a variety of domestic animals including dogs. Several species of Cryptosporidium infecting animals have also been reported in humans highlighting the zoonotic nature of the disease. This prospective cross-sectional study was carried out from January -: May, 20 1 8 in Six Area Councils of the FCT. Three war...
ABSTRACT The risks of humans contracting bovine tuberculosis (BTB) and other mycobacterial infections abound in Nigeria. This could be attributed to the close association between farmers and cattle, unhealthy meat processing practices by butchers, consumption of unpasteurized milk and milk products, and poor knowledge of the disease. The circulating Mycobacterium tuberculosis complex and non-tuberculous mycobacteria in livestock workers and animals are largely unknown. Confirming the sources...
ABSTRACT The African Giant Rat (AGR) recently gained international prominence due to its ability to detect landmines and tuberculosis using olfactory and cognitive cues. However, a striking gap exists in the literature on the neurocellular components that govern these unique abilities. This study investigated and described the morphology of cellular components, useful morphometric parameters and neurogenesis profile of the brain of the AGR across age groups. Forty male AGR comprising 10 neona...
ABSTRACT This study investigates the performance of Claria gariepinus broodstock fed with grasscutter faecal droppings.