List of abbreviations ......................................................................................................................................... 5 List of figures ................................................................................................................................................... 7 List of tables .................................................................................................................................................... 7 Sum...
ABSTRACT Rift valley fever (RVF) is a zoonotic disease caused by Rift Valley fever virus (RVFV) with impact on animal and human health. Vaccines developed against RVF have safety and efficacy concerns and administered by needles posing risks of RVFV transmission. This study reports the safety and immunogenicity of attenuated RVF MP-12 and its recombinant arMP-12ΔNSm21/384 vaccines. A total of 32 sheep, 15 goats and 23 zebu calves were vaccinated with 1x105 plaque forming units (PFU)/ml of M...
ABSTRACT Xn the tropics, hepatitis C virus (BCV) seroprevalence ranges from < 0.2% in whole Africa. A strong association between HCV and hepatitis B surface antigen (jPBPIsAg)-negative chronic liver disease and hepatocellulax carcinoma has been described. Hepatocellular carcinoma (IYCC) 8s one of the mort common cancers among Africans, and in Nigeria by 1970 the'estimated rate was 6.6 per 1Q0,QOO populations per asmum. Sexual tnmsmirsion was regarded as a minor cause of HCV, the degree of whi...