Abstract Introduction: Female Genital Mutilation (FGM) is widespread in Tanzania and poses a risk when women give birth. Objective: To determine the association between FGM and perineal injury among women in labour in Dodoma Methods: A matched case-control study of 364 randomly selected consenting women in labour was conducted in Dodoma Region between January 2017 and June 2018. Controls (no perineal injury) were matched to the cases (with perineal injury) based on maternal age at a ratio 2:1...
ABSTRACT The prevalence of female infertility ranges from 7 to 28% depending on the age of the woman. Although the origin and frequency of infertility vary about 40 to 50% of the aetiology of infertility cases is as a result of female factors. Malaria and the treatment of malaria have being a major challenge for decades. A number of antimalarial drugs have been reported to have anti-fertility actions. Amodiaquine (AQ) is an anti-malarial drug and belongs to a class of drugs known as the 4-ami...
The aqueous root extract of Dalbergia saxatilis (DS) was used to study the pharmacological and toxicity profile of the plant, to ascertain the various medicinal uses and lack of toxicity claims by Traditional Medicine Practitioners. The 24h (up 14 days) acute toxicity and 90-day (plus 14 day reversibility) synchronic toxicity studies were explored to evaluate the toxicity potentials, and as basis for dose selection in the pharmacological studies. DS (50-200 mg/kg) was used to study the centra...
Abstract Pediatric CRC has a poor prognosis compared with adult CRC mainly due to delayed diagnosis. *us, early diagnosis based on a high degree of suspicion could be the most important factor in a more favorable prognosis, especially in patients with predisposing factors. CRC is one of the major causes of cancer-related death globally [1, 2]. *e most common histological subtype of CRC is adenocarcinoma NOS, of which mucinous adenocarcinoma is a distinct subtype and is characterized by abunda...
ABSTRACT Sexually Transmitted Infections (STIs) are infections passed from one person to another during sexual contact though some are also passed from mother to child during pregnancy, birth or while breast feeding. STIs constitute an important public health problem. The early detection and treatment of STIs are important aspects of a comprehensive approach to reducing the spread of HIV. Although public-sector services are available even in the most resource-poor countries, they are not acce...
ABSTRACT BACKGROUND Severe anaemia is prevalent in most African countries and is highly associated with increased morbidity and mortality in under-fives. Globally, iron deficiency is responsible for half of all anaemia, In Africa causes like malaria, hookworm and other helminths, other nutritional deficiencies, chronic infections and genetic conditions prevail and these causes differ from place to place. Exhaustive diagnostic evaluation is needed to establish causes of severe anaemia however...
ABSTRACT Background: A worldwide estimated annual case of cervical cancer is 528,000 and ends with 266,000 annual deaths. In developing countries, it accounts for about 85% for both morbidity and mortality. In sub-Saharan Africa the incidence is 25.2%, mortality 23.2% and five-year prevalence is 27.6%. In Tanzania the rate of cervical cancer is 54.4% per 100,000 people a year. This indicates that, cervical cancer is a public health concern in Tanzania. Objective: assessing clinical profile a...
ABSTRACT Background: Benign prostate hypertrophy (BPH) is a prostatic enlargement associated with the presence of voiding symptoms and/or histological evidence of hyperplasia on biopsy. Transurethral resection of the prostate (TURP) is considered the gold standard management for BPH. Despite being one of the common urological procedures in Tanzania, complications of TURP have not been well explored. There was limited published information on the incidence and prevalence of Benign Prostate Hy...
ABSTRACT BACKGROUND: Escherichia coli (E. coli) is a bacterium that can asymptomatically colonize a woman’s vagina and up to 31% of pregnant women are colonized worldwide. Furthermore, vaginal colonization with E. coli is associated with adverse pregnancy outcomes, such as preterm birth and stillbirth. It is also associated with neonatal sepsis or meningitis when transmitted to the foetus through amniotic fluid or to the neonate during delivery. To date in Namibia data on the colonization a...