Search result: No clinical evidence concerning adverse effects of aluminium, barium or strontium released from GICs were found. A review of the relevant laboratory literature, including a conservative calculation of any potential adverse clinical effect due to aluminium content, concludes that the amount of aluminum that could be leached into the body from glass-ionomer dental fillings is well below the permitted daily dose and almost certainly too small to have a measurable effect. This,...
Search result: No trial could be found. Clinical outcomes: None State of evidence and recommendations: None [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity of results and thus do not replace the need for a full systematic review report to the topic]
Search result: 7 trials were found. Clinical outcomes: The results of the mainly laboratory trials suggest that stannous ions have an inhibiting effect on oral bacteria (particularly when stannous fluoride was compared to sodium fluoride). State of evidence and recommendations: The quality of the existing evidence requires further assessment. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first over...
Search result: Two clinical controlled trials were found. Clinical outcomes: The results suggest no difference in the failure rate of GIC restorations placed after either complete or incomplete removal of infected (soft) carious dentin. State of evidence and recommendations: The quality of the existing evidence requires further assessment. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overvie...
Search result: Four clinical controlled trials were found between the period of 2004 and 2015 (19.11.15). Clinical outcomes: The results show that composite resin performs less satisfactory when compared to amalgam. State of evidence and recommendations: The quality of the existing evidence requires further assessment. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clini...
Search result: One article, reporting on 2 clinical trials, was identified, concerning plaque pH-decrease after sucrose challenge: (a) comparison of CPP-ACP containing paste with no paste; (b) comparison of CPP-ACP containing paste with placebo. Clinical outcomes: The results show a significant reduction in plaque pH fall after sucrose challenge with CPP-ACP containing paste State of evidence and recommendations: The results of both reported trials need to be regarded with caution due to...
Search result: No clinical trials or 2-arm (controlled) trials of any design (in-situ, in-vitro) could be found. Only one single-arm/longitudinal in-situ trial was identified. This trial used the test subjects as control group (without CPP-ACP). Clinical outcomes: The results of this trial showed an increase of the saliva pH in 16 out of 25 subjects after 3 weeks. A change from the initial level of pH 6.6 to the final level of around pH 7.6 was observed. State of evidence and recommendation...
Search result: Ten clinical trials were found and traced concerning high-viscosity conventional GIC. No trials were identified comparing strontium or calcium low-viscosity conventional GIC. All identified trials compared Fuji IX for strontium and Ketac Molar for calcium based GIC. Clinical outcomes: The overall results suggest no difference between Fuji IX and Ketac Molar in the clinical outcomes of: recurrent caries, occlusal wear and colour match. Two of the 10 trials suggest a higher fa...
Search result: Three clinical trials with a laboratory component were found. Clinical outcomes: There appears to be no difference in the pulp response between conventional glass-ionomer cement (C-GIC) and CaOH-cement (CaOH is considered to be the gold standard in pulp treatment due to its high tissue supporting properties. Lack of difference between C-GIC and CaOH suggest high bio-compatibility of C-GIC concerning pulp tissue). State of evidence and recommendations: The current level of c...
Search result: One clinical trial was found. Clinical outcomes: There appears to be no difference in the success rate of both types. State of evidence and recommendations: The current level of clinical evidence to this topic appears to some extent contradictory and may still be limited in quantity and quality. Thus more trials are needed in order to confirm the current results. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the den...
Search result: Five clinical trials were found. Clinical outcomes: There appears to be no difference in the survival rate of both types of restorations. Post-operative sensitivity appears to be reduced for a short-time period after restoration placement when a GIC liner is used. State of evidence and recommendations: The current level of clinical evidence to this topic appears to some extent contradictory and may still be limited in quantity and quality. Thus more trials are needed in orde...
Search result: Two clinical trials were found. Clinical outcomes: There appears to be no difference in the survival rate of both types of restorations after 2 years. State of evidence and recommendations: The current level of clinical evidence to this topic appears to some extent contradictory and may still be limited in quantity and quality. Thus more trials are needed in order to confirm the current results. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s period...
Search result: Four clinical trials were found. The limited number of clinical trials is surprising considering that the topic of GIC/Composite sandwich restorations was very popular 20 years ago. However, the bulk of research studies appeared to be limited to a very large number of laboratory (in-vitro) trials, only. Although important to clarify material characteristics, laboratory trials are unable to provide information how well these restorations really perform in the clinic, particu...
Search result: Three clinical trials were found. Clinical outcomes: The results indicate that additional selective enamel etching does not improve the clinical performance of restorations. State of evidence and recommendations: The current level of clinical evidence to this topic appears to some extent contradictory and may still be limited in quantity and quality. Thus more trials are needed in order to confirm the current results. [‘Preliminary Systematic Literature Searches’ are ba...
Search result: Eleven clinical trials were found. Clinical outcomes: Minor or no improvements are reported when selective enamel etching was used. Selective enamel etching may not pose a hazard in terms of postoperative hypersensitivity. State of evidence and recommendations: The current level of clinical evidence to this topic appears to some extent contradictive and may still be limited in quantity and quality. Thus more trials are needed in order to confirm the current results. [‘Prel...