Medical & Health Sciences

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Medical & Health Sciences Research Papers/Topics

Antimicrobial, Phytochemical and Proximate Analysis of Four Nigerian Medicinal Plants on some Clinical Microorganisms

The increasing incidence of resistance to antibiotics among bacteria currently poses serious clinical and public health threat and has propelled efforts for newer alternatives to alleviate the problem. Extensive search and testing for different plants with potentials for antimicrobial properties is presently considered one of the most feasible options as substitutes to the current regimen of antimicrobials. We tested the antibacterial characteristic and the phytochemical composition of four c...

Phytochemical and Proximate

The purpose of this present study of seven Nigerian medicinal plants is to ascertain the medicinal, phytochemical and proximate constituents of the plants. The plants are .Acacia albida Del,   Anchomanes difformis Engl,   Boscia senegalensis,   Bridelia ferruginea Benth,  Ficus ingens (Miq.) Miq,  Indigofera arrecta   Hochst   and  Moringa oleifera Lam

Comparative Study of the Antibacterial and antifungal Spectrum, Phytochemi

 Piliostigma reticulatum plant found in West Africa. It is an Evergreen shrub with a twisted bole to 9 m high, with a bushy spherical canopy. Bark dark grey to brown, fibrous and corky, slash dark red. Leaves large, thick, leathery, grey-green, 6-12 cm long, Fruit large, long, straight, undulate or twisted and hard, either glabrous or sparsely pubescent, brown, indehiscent, up to 25 cm long, 5 cm wide. Alchonea laxiofolia is a Deciduous, erect to straggling shrub 7m tall. Two extracting solv...

ANTIMICROBIAL ACTIVITY AND PHYTOCHEMICAL COMPOSITION OF CRUDE ETHYL ACETATE EXTRACTS OF ANISOPUS MANNI

 Anisopus mannii(Asclepiadaceae) –is a glabrous twining shrub, strong climber with greenish flower in globose, lateral umbelliform cymes it is widely used as an anti-diabetic agent in Northern and southern Nigerian traditional medicine, Studies were conducted to determine the phytochemical constituents of leaf and bark ethyl acetate extracts of Anisopus mannii and to evaluate its antimicrobial activity, using the agar well diffusion technique using standard phytochemical analysis procedure...

ANTIBACTERIAL SENSITIVITY PROFILE, ISOLATION AND IDENTIFICATI ON OF BACTERIA USING API 20E KITS

The purpose of this research work is to determine the microbiological profile of hospital solid waste dump sites, sensitivity to antibiotic and isolation and identification of the organism using API 20 E kit method of analysis. Microbiological profiling was carried out on hospital solid waste collected from State Specialist Hospital in Ikare-Akoko. The mean total aerobic counts of the bacteria isolated from the solid waste samples collected from six (6) units in the hospital were 5.0 x 104 cf...

Effects of vernonia amygdalina on neurobehavioral activities of albino rats

         TABLE OF CONTENTS Preface Certification Dedication Acknowledgements Table of contents List of tables List of figures Abstract CHAPTER ONE 1.       Introduction 1.1     cannabis sativa 1.2     cannabis and cannabinoids 1.3     Vernonia amygdalina CHAPTER TWO 2        Literature Review 2.1     Effects of aqueous extract of Vernonia amygdalina and cannabis sativa on neurobehavioral activities. 2.2     Decreasing or disabling neuronal functions....

Critical evaluation of Community participation approach in addressing maternal and child nutrition in Nigeria Nutritional Policy

Malnutrition is a global challenge especially in the developing countries. Nigeria is the tenth highest country with under-five mortalities globally and the third highest country with stunted growth among children (43%). In order to reduce the malnutrition rate, the National Strategic Plan of Action for Nutrition (NSPAN) was adopted in 2014. This article critically evaluated three delivery processes that may promote community participation in maternal and, infants, young child feeding nutriti...

Effects of aqueous extract of Basella alba leaves on haematological and biochemical parameters in albino rats

The effects of the aqueous leaf extract of Basella alba on haematological and biochemical parameterswere studied in Wistar strain albino rats. Twenty four (24) Wistar strain albino rats were randomlydistributed into four groups of six (6) rats each. Group I rats served as control and received 10 ml/kg ofnormal saline, while group II, III and IV received 60, 80 and 100 mg/kg of aqueous leaf extract of B. alba,respectively, for two weeks. Administration of the extract was done orally. At the en...

Virgin Coconut Oil: Remedial Effects on Renal Dysfunction in Diabetic Rats

Renal dysfunction is nowa prevalent complication of diabetesmellitus. Therefore, this study was carried out to evaluate the remedialeffects of virgin coconut oil (VCO) on renal dysfunction in diabetic rats. Fifteen albinoWistar rats were divided into 3 groups thatcomprise normal control group (Group I) and diabetic control group (Group II) fed with normal rat chows and a diabetic test group(Group III) fed with 10% VCO diet. Group II and Group III were made diabetic by single intraperitoneal i...

Dietary Consumption of Virgin Coconut Oil Ameliorates Lipid Profiles in Diabetic Rats

Virgin coconut oil (VCO) is a saturated fat with promising antidiabetic properties but its ameliorative effect on lipid profilesin diabetics is rarely reported. Therefore, in this study, a total of fifteen (15) male rats weighing 200–250 g were divided into 3experimental groups (𝑛 = 5).Group I (control) andGroup II (diabetic control group) were fed a normal rat chowwhile Group III(diabetic test group) was fed a 10% VCO diet for 3 weeks. Group II and Group III were made diabetic by intrap...

Virgin Coconut Oil (VCO) supplemented diet ameliorates blood glucose, renal tissue and antioxidant enzymes in diabetic rats

Untreated hyperglycaemia leads to kidney damage through oxidative stress of the kidney tissues with resultantcompromise of the antioxidant enzymes. According to research, Virgin Coconut Oil (VCO) has been reported tohave hypoglycaemic and anti-diabetic properties. Therefore, this study was designed to investigate theameliorative effects of VCO supplemented diet on blood glucose, renal tissues and antioxidant enzymes indiabetic rats. The study was carried out on fifteen male rats weighing 150 ...

Virgin coconut oil dietary consumption ameliorates abnormal haemostatic parameters in diabetic rats

Introduction: Virgin coconut oil (VCO), a saturated fat,has been reported to have anti-diabetic properties and thereis dearth of information on its potency to correct abnormalhaemostatic parameters associated with diabetic patients.Objectives: Therefore, this study was carried out toinvestigate effect of VCO consumption on abnormalhaemostatic parameters in diabetic rats.Materials & Methods: A total of fifteen (15) male ratsweighing 200–250g were divided into three (3) experimentalgroups: No...

Long Term Consumption of Coconut Oil Diet Increased Anxiety Related Behaviour in CD1 Mice

The effect of prolonged consumption of virgin coconut oil (VCO) diet on anxiety was assessed in CD1 mice using the Open field (OF), Elevated plus maze (EPM) and Light/dark box (LD box) tests. Thirty male CD1 mice (28.4-32.5 g bw) divided into 3 groups (n=10 each) were given normal rodent chow (control), 5% (w/w) and 20% (w/w) VCO diet respectively and water ad libitum for 23 days. The OF test showed increased grooming (p< 0.05) in both 5% and 20% VCO groups versus control, and higher Freeze f...

Pattern of intensive phase treatment outcomes of multi-drug resistant tuberculosis in University of Port Harcourt Treatment Centre

ABSTRACT _________________________________________________________ Background: Multi-drug resistant tuberculosis (MDR-TB) is currently a global menace and poses significant risk to persons living in Sub-Saharan Africa. It occurs largely from failure of conventional treatment of tuberculosis. Its emergence further threatens TB control and prevention. Objective: This study was conducted to determine the pattern of intensive-phase treatment outcomes among hospitalized MDR-TB patients in Unive...

Prevalence of urinary schistosomiasis and water contact activities as risk factor in Wowyen community

This study assessed the prevalence of urinary schistosomiasis and water contact activities as associated risk factor in Wowyen community. A total of 620 subjects comprising of 300 male and 320 female subjects were analyzed. The prevalence was achieved by standard urine filtration technique. One way analysis of variance (ANOVA) and paired t-test was carried out using software SPSS Statistical version 20. The result confirmed an overall (37.91%) prevalence of infection. On the trait of ages, di...


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