Hiv/Tb Co-Infection In The Development Of Drug Resistant Tb At Three Major Referral Hospitals In Southern Ghana

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ABSTRACT 

Introduction: Tuberculosis (TB) remains an important cause of human suffering and death. The impact of Human immunodeficiency virus (HIV) on TB, drug resistant TB (DR-TB) and the implications for TB control, has been acknowledged as a major public health challenge. The influence of HIV/TB co-infection in the development of DR-TB has not yet been fully investigated in this part of the world. 

Objective: The aim of this study was to determine the role of HIV/TB co-infection in the development of drug resistant TB at three major referral hospitals in Southern Ghana. 

Methodology: A descriptive cross-sectional analysis of TB data at the Greater Accra Regional Hospital, the Korle-Bu Teaching Hospital and the Eastern Regional Hospital was conducted using databases of their TB Registry spanning the period of February 2013 to December 2017. 

Results: A total of 9722 Tuberculosis (TB) patients diagnosed were reviewed. HIV prevalence was significantly high 30.0% (p

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