ABSTRACT
Insecticide resistance affects the re-emergence of vector borne diseases and their control. Resistance to insecticides poses a risk to compromise the role of chemical vector control as a component of the integrated vector management. The kdr (knock down resistance) allele is characterised by a single base pair substitution causing a change from leu to phe (West Africa) or leu to see (East African) in codon 1014 of the voltage sensitive sodium channel protein sequence. In Kenya the knockdown resistance gene (kdr), a target site insensitivity based L1014S mutation to both DDT and pyrethroids confers resistance to these insecticides and has been reported in some Anopheles gambiae strains.
, M (2024). Molecular Analysis of the Knockdown Resistance (kdr) Gene in the Anopheles Gambiae s.l. and Anopheles Funestus Populations in Kenya. Afribary. Retrieved from https://tracking.afribary.com/works/molecular-analysis-of-the-knockdown-resistance-kdr-gene-in-the-anopheles-gambiae-s-l-and-anopheles-funestus-populations-in-kenya
, Mutunga "Molecular Analysis of the Knockdown Resistance (kdr) Gene in the Anopheles Gambiae s.l. and Anopheles Funestus Populations in Kenya" Afribary. Afribary, 27 Feb. 2024, https://tracking.afribary.com/works/molecular-analysis-of-the-knockdown-resistance-kdr-gene-in-the-anopheles-gambiae-s-l-and-anopheles-funestus-populations-in-kenya. Accessed 23 Nov. 2024.
, Mutunga . "Molecular Analysis of the Knockdown Resistance (kdr) Gene in the Anopheles Gambiae s.l. and Anopheles Funestus Populations in Kenya". Afribary, Afribary, 27 Feb. 2024. Web. 23 Nov. 2024. < https://tracking.afribary.com/works/molecular-analysis-of-the-knockdown-resistance-kdr-gene-in-the-anopheles-gambiae-s-l-and-anopheles-funestus-populations-in-kenya >.
, Mutunga . "Molecular Analysis of the Knockdown Resistance (kdr) Gene in the Anopheles Gambiae s.l. and Anopheles Funestus Populations in Kenya" Afribary (2024). Accessed November 23, 2024. https://tracking.afribary.com/works/molecular-analysis-of-the-knockdown-resistance-kdr-gene-in-the-anopheles-gambiae-s-l-and-anopheles-funestus-populations-in-kenya