Prognostic Factors For Overall Survival Of Patients With Prostate Cancer In Kyadondo County, Uganda

ABSTRACT

Prostate cancer (PCa) is the leading cause of cancer

morbidity

and mortality in elderly men worldwide. It is the

second and fih leading cause of cancer-related deaths

among men in developing and developed countries

respectively

[1]. Globally, black men are more affected than

whites. Miller et al. [2] reported the incidence rates of PCa

for black American men and those from Asia particularly

in India, was 228.7 and 141.0 per 100,000 respectively [3].

Uganda is one of the countries in the southern Sub-Saharan

Africa (SSA) with very high incidence rate of PCa. In 1990s,

PCa in Uganda was among the cancers with highest prevalence

[4]. Also in 2011, Uganda was reported to have PCa

incidence rate of 38.1 per 100, 000 [5]. is high incidence

rate is also reflected by the poor survival of PCa patients in

the country. Gondos and associates [5] reported a very low

5-year overall survival rate of patients with PCa of about

49.6%. In a study by Wabinga et al. [6] reported that, the

5-year age-standardized relative survival rates for prostate

cancer in Uganda was 46%.

Because of scarcity of follow-up data of cancer patients in

developing countries in which Uganda is included, this contributes

to shortage of studies involving survival analysis.

Moreover, even availability of survival data of patients in

Uganda and other countries in the Sub-Saharan Africa where

PCa is overwhelming, is still a problem that needs measures

to be addressed [7, 8].

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