Response Of Intravenous Fluconazole Monotherapy During The Induction Phase In The Treatment Of Cryptococcal Meningitis In Hiv/Aids Adult Patients In Dodoma, Tanzania

ABSTRACT

Background: Cryptococcal Meningitis (CM) is the most common central nervous system (CNS) manifestation encountered in advanced HIV/AIDS patients. In low resource settings, it has high documented mortality rate at 2 and 10 weeks because of poor management of intracranial pressure (ICP), untimely ART initiation, and inappropriate antifungal regimen used during the induction phase.

Objective: To evaluate the response of intravenous fluconazole monotherapy during the induction phase in the treatment of CM in HIV/AIDS adult patients in Dodoma.