Aim: To assess the association between single infection and co-infection status of the two
parasites with hematologic profiles in school children.
Methods: A cross-sectional epidemiological survey was carried out on a total of 202 school
children between ages 6-18 years (mean age 11.5 ± 2.6 years). Urine and blood samples
were collected by standard methods for concurrent microscopic diagnosis of Schistosoma
haematobium and Plasmodium falciparum infections respectively. The following hematologic
parameters; hematocrit, hemoglobin, neutrophils, leukocytes, lymphocytes and eosinophils
were determined.
Results: The prevalence of single infection was 52.0% and 59.9% for S. haematobium and P.
falciparum respectively, while 28.2% individuals were infected with the two parasites. The
prevalence of abnormal hematologic profiles in the subjects was not associated with
infection status (single or co-infection) (P > 0.05). There were however higher risk of
developing low hemoglobin concentration with P. falciparum (Prevalence = 71.0%, OR= 6.0,
CI = 3.2-11.0) with children with S. haematobium infection being weakly predisposed to
developing abnormal neutrophils (Prevalence = 53.3%, OR = 1.3, CI = 0.7-2.3). Low he-
moglobin associated risk in single infection with S. haematobium (OR= 2.0, CI = 1.1-3.6) was
increased with co-infection with P. falciparum (OR = 4.0, CI = 1.8-8.7). There seemed to be
no difference in abnormal leukocytes and eosinophils associated risk in the three infection
categories.
Conclusions: There were variations in Schistosoma and malaria parasite induced hematologic
pathologies and more studies are needed to unravel the underlying mechanisms in such
variations.
Oyeyemi, O. (2018). Schistosoma haematobium and Plasmodium falciparum single and concomitant infections; any association with hematologic abnormalities?. Afribary. Retrieved from https://tracking.afribary.com/works/schistosoma-haematobium-and-plasmodium-falciparum-single-and-concomitant-infections-any-association-with-hematologic-abnormalities
Oyeyemi, Oyetunde "Schistosoma haematobium and Plasmodium falciparum single and concomitant infections; any association with hematologic abnormalities?" Afribary. Afribary, 24 Oct. 2018, https://tracking.afribary.com/works/schistosoma-haematobium-and-plasmodium-falciparum-single-and-concomitant-infections-any-association-with-hematologic-abnormalities. Accessed 18 Dec. 2024.
Oyeyemi, Oyetunde . "Schistosoma haematobium and Plasmodium falciparum single and concomitant infections; any association with hematologic abnormalities?". Afribary, Afribary, 24 Oct. 2018. Web. 18 Dec. 2024. < https://tracking.afribary.com/works/schistosoma-haematobium-and-plasmodium-falciparum-single-and-concomitant-infections-any-association-with-hematologic-abnormalities >.
Oyeyemi, Oyetunde . "Schistosoma haematobium and Plasmodium falciparum single and concomitant infections; any association with hematologic abnormalities?" Afribary (2018). Accessed December 18, 2024. https://tracking.afribary.com/works/schistosoma-haematobium-and-plasmodium-falciparum-single-and-concomitant-infections-any-association-with-hematologic-abnormalities