CHEMOPROTECTIVE ROLES OF DIPHENYL DISELENIDE(DPDS) ON CHLORPYRIFOS(CPF)- INDUCED NEUROTOXICITY IN MID-BRAIN OF MALE RATS
ABSRACT Chlorpyrifos [CPF; O,O-diethyl O-(3,5,6-trichloro-2-pyridinyl) phosphorothionate] is a widely used organophosphate pesticide that is known to be toxic to the environment and to living beings. It affects several organs of the body especially the brain leading to impairment of normal functioning of the body. Diphenyl diselenide (DPDS), an organsoselenium compound is the simplest of the synthetic diaryldiselenides. Studies have shown that DPDS exhibits anti-inflammatory and antioxidant e...