ABSTRACT Entrohemorrhagic Escherichia coli O157:H7 is a major food borne pathogen causing severe disease in humans worldwide. Healthy cattle are the reservoir of Escherichia coli O157:H7, and bovine food products and fresh produce contaminated with bovine waste are the most common source for disease out breaks in the United States. Escherichia coli O157:H7 also survives well in the environment. The abilities to cause human disease, colonize the bovine gastrointestinal tract, and require tha...