ABSTRACT An in vivo study was carried out to determine the antitrypanosomal effects of methanolic extracts of the stem barks of Nauclea diderrichii (Merr) and Spathodea campanulata using Trypanosoma brucei brucei- infected mice. The antitrypanosomal effects of these plant parts were determined using rapid “matching” method. The effect of the extracts in vivo was determined based on the changes in the level of parasitaemia, PCV and weights of the mice. The stem bark extract of Spathodea...