Medical & Health Sciences

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Research Papers/Topics Medical & Health Sciences

Cariostatic effect of conventional GIC versus compomers [October 03, 2015]

Search result: There is a lack of clinical studies to this topic: Only three clinical trials were found and traced. Clinical outcomes: The results are conflicting or suggest no difference between conventional GIC and Compomers in regard to their anticariogenic effects. State of evidence and recommendations: The quality of the existing evidence requires further assessment. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental lit...

Cariostatic effect of resin-modified GIC (RM-GIC) versus compomers [October 03, 2015]

Search result: Twelve clinical trials were found and traced. Clinical outcomes: The overall results suggest no difference between RM-GIC and Compomers in regard to their anticariogenic effects. State of evidence and recommendations: The quality of the existing evidence requires further assessment. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are ...

Antibacterial effect of GIC versus composite resin [October 03, 2015]

Search result: One clinical trial was found and traced concerning resin-modified GIC (RM-GIC). The material was Fuji II LC (compared to: Tetric Flow and Helioseal F). No trials were identified comparing conventional GIC (C-GIC) with composite resin. Clinical outcomes: The overall results suggest a higher antibacterial effect for RM-GIC up to 6 months. State of evidence and recommendations: All evidence from one clinical, controlled trial. This is still an emerging topic and the quality of ...

MI Paste PLUS effect to prevent white spot lesions associated with orthodontic treatment [November 03, 2015]

Search result: Three contradicting clinical trials were found so far. Clinical outcomes: Some results show that MI Paste Plus appears more effective in reducing white spot lesions than placebo and fluoride varnish after 3 months, while other results suggest that its effect appears to be equal to that of normal home care after 2 months. State of evidence and recommendations: The quality of the existing evidence requires further assessment. [‘Preliminary Systematic Literature Searches’ ar...

What is the failure rate of GIC restorations placed after incomplete removal of infected carious dentine? [November 23, 2014]

Search result: Two clinical controlled trials were found. Clinical outcomes: The results suggest no difference in the failure rate of GIC restorations placed after either complete or incomplete removal of infected (soft) carious dentin. State of evidence and recommendations: The quality of the existing evidence requires further assessment. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overvie...

How do both Strontium and calcium-based GIC compare clinically? [November 20, 2014]

Search result: Ten clinical trials were found and traced concerning high-viscosity conventional GIC. No trials were identified comparing strontium or calcium low-viscosity conventional GIC. All identified trials compared Fuji IX for strontium and Ketac Molar for calcium based GIC. Clinical outcomes: The overall results suggest no difference between Fuji IX and Ketac Molar in the clinical outcomes of: recurrent caries, occlusal wear and colour match. Two of the 10 trials suggest a higher fa...

Pulp response conventional GIC versus Calcium hydroxide (CaOH) cement [November 20, 2014]

Search result: Three clinical trials with a laboratory component were found. Clinical outcomes: There appears to be no difference in the pulp response between conventional GIC and CaOH-cement (CaOH is considered to be the gold standard in pulp treatment due to its high tissue supporting properties. Lack of difference between C-GIC and CaOH suggest high biocompatibility of C-GIC concerning pulp tissue). State of evidence and recommendations: The current level of clinical evidence to this top...

Survival rate of restorations with GIC cavity liners versus GIC restorations [November 17, 2014]

Search result: One clinical trial was found. Clinical outcomes: There appears to be no difference in the success rate of both types. State of evidence and recommendations: The current level of clinical evidence to this topic is still limited in quantity and quality and more trials are needed in order to confirm these results. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existi...

Survival rate of restorations with GIC cavity liners versus restorations with no-GIC liners [November 17, 2014]

Search result: Five clinical trials were found. Clinical outcomes: There appears to be no difference in the survival rate of both types of restorations. Post-operative sensitivity appears to be reduced for a short-time period after restoration placement when a GIC liner is used. State of evidence and recommendations: The current level of clinical evidence to this topic is still limited in quantity and quality and more trials are needed in order to confirm these results. [‘Preliminary Syst...

Restoration longevity of conventional high - viscosity GIC restorations versus direct composite filings [November 14, 2014]

Search result: Two clinical trials were found. Clinical outcomes: There appears to be no difference in the survival rate of both types of restorations after 2 years. State of evidence and recommendations: The current level of clinical evidence to this topic is still limited in quantity and quality and more trials are needed in order to confirm these results. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and pr...

Failure rates of direct composite versus GIC/Composite sandwich restorations [November 14, 2014]

Search result: Four clinical trials were found. The limited number of clinical trials is surprising considering that the topic of GIC/Composite sandwich restorations was very popular 20 years ago. However, the bulk of research studies appeared to be limited to a very large number of laboratory (in-vitro) trials, only. Although important to clarify material characteristics, laboratory trials are unable to provide information how well these restorations really perform in the clinic, particu...

Etch-rinse systems with and without selective enamel etching [November 10, 2014]

Search result: Two clinical trials were found. Clinical outcomes: The results indicate that additional selective enamel etching does not improve the clinical performance of restorations. State of evidence and recommendations: The quality of the existing evidence requires further assessment. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited...

Selective enamel etching effect on clinical performance of selfetch / self-adhesive systems [November 4, 2014]

Search result: Nine clinical trials were found. Clinical outcomes: Minor or no improvements are reported when selective enamel etching was used. Selective enamel etching may not pose a hazard in terms of postoperative hypersensitivity. State of evidence and recommendations: The current level of clinical evidence to this topic is still limited in quantity and quality and more trials are needed in order to confirm these results. [‘Preliminary Systematic Literature Searches’ are based on S...

Advantages of Self-etch versus Etch-and-rinse systems [November 4, 2014]

Search result: Eight articles reporting on 4 clinical trials after different follow-up periods were found. Clinical outcomes: The results indicate no difference in retention and anatomic form of restorations after 1 – 3 years. Marginal adaptation appears to be superior for etch-and-rinse systems after 1 – 2 years and no difference was found after 3 years. Marginal discoloration is significantly more observed for (1-step) self-etch systems. Post-operative sensitivity was the same for bo...

Resin infiltration to stop carious lesion progression [November 3, 2014]

Search result: Eight clinical studies were found. Clinical outcomes: The results suggest efficacy of resin-infiltration technique to stop caries progression and to improve aesthetic appearance of white spot lesions (WSL). However, discomfort levels appear to be higher than with other noninvasive interventions. State of evidence and recommendations: The quality of the existing evidence requires further assessment. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s peri...


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