ABSTRACT Background: Approximately 2.37 billion people Jive in areas at risk for transmission Of pfalciparum malaria, mainly in sub-Saharan Africa (Hay, et al., 2009). Combination Artemether/Lumefantrine (Coartem, Riamet, and Falcynate-LF) is a fixed dose Artemisininbased combination therapy (ACT) indicated for the treatment of acute uncomplicated Plasmodium Jalciparum malaria. It is an effective and well tolerated treatment providing high cure rates even in areas with multi-drug resistan...
ABSTRACT Background Despite the fact that herbal medicines are used by 80% of the World's population (WHO, 2002) and are the main source of health care in the rural communities and the most preferred form of treatment of HIV-related symptoms (Orisatoki and Oguntibeju, 2010), less than 10% of herbal products in the world market are truly standardized to a known active and/or toxic components (Winston et al., 2007). Study carried out in Western Uganda reported 32.8% of same-day use of herbal m...
Abstract A cross sectional study was conducted in Bushenyi district to review the side effects, adverse effects and the process of collecting herbal medicines between September 2013 and February 2014. The study found out that traditional herbs were being widely used in Bushenyi district in the treatment of malaria, cough, vaginal dryness, abdominal cramps, erectile dysfunction and fevers most frequently than other conditions. The study also found that the most common side effects were nausea ...
ABSTRACT Backgrmmd: More than 50% of all medicines are irrationally used in the world. Rational use of medicines (RUM) means that the right patient receives the right drug, in the right dose, for the right duration, and at the lowest cost for him/her and the community. In a nutshell treatment must follow the standard treatment guidelines of that area. In this case Uganda, the Uganda Clinical Guidelines for treatment of Common Infections is used. The problem of rational use is even most dire w...
Table of Contents DECLARATION ............................................................................................................................................ i ACKNOWLEDGEMENTS .......................................................................................................................... ii ABBREVIATIONS ...................................................................................................................................... vi CHAPTER ONE: INTRODUCTION ......
ABSTRACT Background: Prescription practice is health care service implemented by a physician or other medical practitioner in the fonn of instructions that govern the plan of care for an individual patient; prescription practice may include orders to be performed by a patient caretaker, nurse, pharmacist or other therapist. Prescription is physician's order for the preparation and administration of a drug or device for a patient. A prescription has several parts. They include the superscripti...
ABSTRACT Introduction/Objectives: Fluegge a virosa grows wild in tropical Africa, Arabian Peninsula, tropical Asia, Japan, Australia and Polynesia, and it can also be domesticated. The different parts of the plant have many folkloric usage for diverse ailments including pain, fever, malaria, sexual dysfunction, diabetes, epilepsy, antiarrhythmic, HIV -related illness among many others. The root is claimed to be the most potent part of the plant. In view of the claimed therapeutic potentials, ...
AB ST R ACT Physico-chcmical analyses of t h e surface waters of the lower reaches of the River Niger were carried out for a per iod of one year ( ~ p r i l1 988 - March 1989) covering both t h e rainy and dry seasons t o e ; t a b l i s h Levels of various pollutants and t o study t h t , contribut ions made by the major t r i b u t a r i e s ~ n udrb an a c t i v i t i e s to the gross pollution level. Cerzain physico-chemical properties such as BOD, COD, o i l and grease, conductiv...
ABSTRACT The aim of the present study was to investigate the physicochemical equivalence and compare the dissolution rate of thirteen brands of metronidazole tablets collected from retail pharmacies in Nigerian markets. This study sought to apply the BCS biowaiver requirements to assess the equivalence of commonly interchanged generic Metronidazole tablets with their innovator product in Nigeria. Solubility of active pharmaceutical ingredients (API) has always been a concern for formulators,...
INTRODUCTION In pharmaceutical sciences, microspheres have been extensively studied for use as drug delivery systems, where they have been shown to protect sensitive drugs from enzymatic degradation and allow controlled release, and tissue targeting of the formulated drug. Starch modification, can be used to tailor starch to specific applications. Pantoprazole, a proton pump inhibitor which suppresses the acid production by inhibiting the H+ K+ATPase. In this study, M. pruriens starch, a loc...
ABSTRACT PURPOSE: To investigate the effectiveness of three natural gums, namely albizia, cissus and khaya gums, as excipients for the formulation of ibuprofen microbeads. METHODS: Ibuprofen microbeads were prepared by the ionotropic gelation method using the natural gums and their blends with sodium alginate at various concentrations using different chelating agents (calcium chloride, zinc chloride, calcium acetate and zinc acetate) at different concentrations. Microbeads were assessed ...
ABSTRACT Malaria is a major public health disease. About 90% of all malaria deaths globally occur in Sub- Saharan Africa where Nigeria is located. Children are particularly susceptible resulting in high mortality. Mothers stay at home to care for children with malaria, thereby increasing absenteeism resulting in economic loss at the micro and macro levels. World Health Organization (WHO) in an attempt to ensure prompt treatment of uncomplicated childhood malaria, introduced home management o...
ABSTRACT Based on the ethnomedicinal use and belief that Stachytarpheta jamaicensis (SJ) can increase milk supply in lactating women, experimental studies were carried out to determine the effect of crude methanol extract (CME) and fractions of SJ leaves on serum PRL levels. The pharmacognostic standards, preliminary phytochemical analysis and acute toxicity study were also carried out. The fresh leaves were collected, cleaned, air-dried and pulverized. A photomicroscope was used in the quali...