Medical & Health Sciences

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Medical & Health Sciences Research Papers/Topics

Potential for the Prediction of Prostate Cancer Risk Using Haplotypes of Exon1 Of Klk2 Gene

ABSTRACT Prostate cancer is the third most common cancer in Nigeria and the most underscreened cancer in Nigeria. It is the commonest type of cancer in men of African origin. Most prostate cancer cases in Nigeria are detected at the metastatic stage. The daily pick up of new cases is on the increase especially in tertiary hospitals with most men having advanced and high grade disease high who never gone for medical treatment. PSA testing lacks the ability to characterize prostate disease mole...

Sonographic Assessment of Urolithiasis in University of Abuja Teaching Hospital, Nigeria.

ABSTRACT Background. The prevalence of urolithiasis varies according to geographic areas. Urolithiasis is the third most common urological disease with many complications including renal failure. The prevalence is on the rise in Nigeria due to several epidemiological factors including high environmental temperature. There is paucity of documented scientific study on the prevalence of urolithiasis in the University of Abuja Teaching Hospital within the Federal Capital Territory, Nigeria. Objec...

Economic Burden, Payment Strategies and Payment Coping Mechanism Among Type2 Diabetic Patients Attending a Tertiary Health Institution in Abia State, South East Nigeria

ABSTRACT Diabetes is a chronic life- long illness that affects the quality of life, requiring close monitoring and control. Diabetics have high risk for high economic burden (direct and indirect health costs) and catastrophic expenditure where healthcare costs are paid out of pocket. This study determined the economic burden and assessed the payment strategies and payment coping mechanisms of type 2 diabetic patients attending Out- Patient Department of Federal Medical Centre (FMC) Umuahia, A...

Assessment of the Nutritional Status, Care and Support of People Living with Hiv/Aids in Nsukka Local Government Area, Enugu State

ABSTRACT The nutritional status, care and support of people living with HIV/AIDS (PLWHIV/AIDS) in Nsukka L.G.A of Enugu State was studied at Bishop Shanahan Hospital. The hospital is a HIV counseling and testing (HCT) centre. Descriptive and laboratory analysis were adopted for the study. A total of two hundred and forty three respondents only constituted the sample for the study. Questionnaire, anthropometry, biochemical tests and proximate analysis of foods eaten by PLWHIV/AIDS were the ins...

Prevalence of Risk Factors Associated with Cardiovascular Diseases Among Adults Working in Federal Government Establishments in Umuahia, Abia State Nigeria

ABSTRACT This study assessed the prevalence of risk factors associated with cardiovascular diseases among adults working in Federal Government Establishments in Umuahia Abia state, Nigeria. Two hundred adults randomly selected in the establishments participated in the study. Intervieweradministered questionnaire was used to obtain information on respondents’ socio-economic characteristics, food frequency and some lifestyle practices. The anthropometric measurements of the respondents were t...

Predicting Intestinal Permeation of Drugs Through Neural Network Analysis Based on Five Molecular Descriptors

ABSTRACT The oral route is generally preferred for drug administration because of its ease and good patient compliance. In the search for new drugs for oral administration a major problem encountered is obtaining drug structures which, as well as being potent in viiro, possess favourable pharmacokinetic profiles which enable them to pass easily through the relevant body membranes, especially the gastrointestinal epithelia to effect their action. However, many of the compounds derived from com...

Assessment of Staphylococcal Nosocomial Infections in National Orthopedic Hospital, Enugu

ABSTRACT In a comprehensive work to assess staphylococcal nosocomial infections in patients in National Orthopaedic Hospital, Enugu (NOHE), Nigeria and to assess the possible contribution of healthcare workers and fomites, a study was carried out between May 2013 and June 2014. This involved the analysis of a total of 578 samples, 200(35%) comprising of 100 in-patients and 100 healthcare workers ) and 378 samples collected from different fomites within the theatre/ wards. Human samples (wound...

Factors Restraining Choice of Nursing as a Career Among Male Sssiii Students in Enugu Urban

ABSTRACT The various institutions offering nursing programmes have continued to witness very low male enrollment while female enrollment continue to increase. This situation created the problem of sex stereotype, gender bias and lack of professional autonomy which could have been addressed if men were well represented in nursing profession. This work therefore was aimed at determining the factors restraining choice of nursing as a career among male SSSIII students in Enugu Urban. The specific...

Formulation and Optimization of Artemether and Lumefantrine Calcium Alginate Capsules Using Inverse Gelation Technique

ABSTRACT Poorly water-soluble drug candidates are associated with dissolution, absorption and bioavailability challenges. Consequently, poor solubility and non-reproducible absorption from the gastrointestinal tract following oral administration constitute a biopharmaceutical concern to dosage form design and formulation. The use of lipid-based formulations to address this concern has been the choice of many scientists in the drug delivery domain. Artemether and Lumefantrine the drugs investi...

Knowledge and Management of Menstruation and Menstrual Problems Among Urban and Rural Secondary School Girls in Enugu East Local Government Area

ABSTRACT In many societies menstruation is not openly discussed in some families, school and communities leading to a very big gap in knowledge about menstruation and menstrual problems. This gap equally poses problems on issues about menstrual hygiene, menstrual problems and management of those problems. In addition to inadequate information, girls need access to hygienic absorbent sanitary products, water, good toilets that ensure privacy and disposal facilities which can in the long run, p...

Evaluation of the Immunomodulatory Activities of the Aqueous Extract and the Beta–D-Glucan-Rich Polysaccharide Fraction of Pleurotustuberregium(Pleurotaceae)

ABSTRACT Mushroom cuisines are global delicacies and have been used for decades, not only as food, but mostly for the health benefits which are claimed or scientifically proven. The present study explored the immunomodulatoryactivites of the hot aqueous extract of a local oyster mushroom, Pleurotustuberregium (Fr.) Singer (Pleurotaceae) (PT) and its β–D-Glucan-Rich Polysaccharide fraction (BGP).The effects of the aqueous extract (PT) and the β–D-Glucan-Rich Polysaccharide fraction (BGP)...

Sonographic Assessment of Renal Parenchymal and Medullary Pyramid Thicknesses Among Healthy Children in Selected Schools in Enugu, Nigeria

ABSTRACT Renal parenchymal thickness (RPT) and renal medullary pyramid thickness (MPT) are important renal size parameters and there is no existing ultrasound normogram for RPT and MPT among children in our locality. Thus, this study was aimed at establishing normal values for RPT and MPT among children in Enugu metropolis; establishing the relationship between RPT and MPT with age, height, body weight, body mass index (BMI) and body surface area (BSA) among the subjects; establishing the rel...

Knowledge, Attitude and Practice of Care of the Elderly Patients Among Health Workers in University of Calabar Teaching Hospital Calabar, Cross River State, Nigeria.

ABSTRACT With the global trend towards an increasing aging population, there is a corresponding increase in the health problems associated with elderly population especially in developing Countries including Nigeria. With this increase in the growth of the aging population, the number of people that will need health care will undoubtedly increase, which motivated this study. The study was aimed to assess the level of knowledge, attitude and practice of care of the elderly patients among healt...

Food Consumption Pattern, Anthropometric Indices and Micronutrient Status of Children Aged 6 – 59 Months in Kaduna State, Nigeria

ABSTRACT The study was undertaken to assess food consumption pattern, anthropometric and micronutrient status of children aged 6-59 months in Kaduna state. A cross sectional survey design was used. A multi stage sampling technique was used to select the subjects for the study. In the first stage, two Local Government Areas were selected from each of the three senatorial districts using simple random sampling procedure. This gave a total of 6 Local Government Areas. In the second stage, purpos...

Association Between Women’s Status and Use of Maternal Health Care Services of Primary Health Centres in Nando, Anambra East L.G.A, Anambra State

ABSTRACT The study examined the association between women’s status and utilisation of maternal health care services of primary health care centres in Nando, in Nando, Anambra east L.G.A of Anambra State. Five objectives were developed. A cross sectional descriptive research design was used. The study population consisted of women of child bearing age (15-49years) who had given birth in the last five years. A sample size of 500 participants was used after using the formula for estimating sam...


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