Abstract In this study computational chemistry, drug design and docking tools were employed to discover a new class of fluoroquinolone derivatives. Fifty eight compounds were designed and made to dock into the active site of a selected receptor (4eru and 1jij); which was retrieved from protein data bank. It was found that modifications in the molecular structure of the core skeleton of fluoroquinolones structure highly affect at biological activity.It was clearly observed positions 2, 3 and 4...
ABSTRACT Chlamydia trachomatis infections are the most common bacterial cause of sexually transmitted diseases (STDs) in the world. This study was to investigate the prevalence of Chlamydia trachomatis infection amongst students of Federal university Oye-Ekiti, Ekiti State, Nigeria. Urine samples were collected from ninety four participants and were screened using the microwell ELISA Chlamydia trachomatis kit - Swab/Urine . (Golden Bio Technologies Corp, USA). Out of 94 patients screened, 26...
Abstract We Show the uniqueness of the norm on the Lebesgue space of the compact group. We give some applications of the property of Kazhdan to the method of automatic continuity. We determine the similarity of quasinilpotent operators. The symmetric Meixner- Pollaczek polynomials and a system of orthogonal polynomials with Hardy spaces for the strip are considered. We investigate the behaviour of the Lebesgue space of the integral means of the analytic functions and the vector- valued BMOA ...
Abstract Two types of hibiscussabdariffa L were prepared (red and white) in the form of powder respectively and the samples were exposed to the XRF meter to identify elements and their concentrations of the samples. Also the samples were exposed to X-ray to study the crystal structure. It was found that the material was amorphous. Also some of the samples were dissolved in cold and hot water in the form of a solution and were characterized by UV-VIS spectrometer to study the absorbance ...
ABSTRACT Cr (VI) is a well-known highly toxic metal. This project focuses on the removal of Cr (VI) from contaminated water using activated carbon entrapped in calcium alginate beads. Activated carbon used for this work was prepared from an organic waste material called walnut shell by carbonization using phosphoric acid as an activating agent. 0.5g of activated carbon was added to 10mL of 4% sodium alginate solution.The mixture was promptly dropped into 3.5% aqueous solution of calciu...
ABSTRACT Limestone, glauconite, ferruginized sandstone and shale samples were obtained from the mapped newly exposed part of the Dangote Cement quarry located in Ibese, eastern Dahomey Basin, Nigeria. The Paleocene-Eocene Akinbo and Ewekoro Formations were studied, logged and sampled from the Northern (NM) and Southwestern (SWM) sections quarried to depths of about 12m and 23m respectively. Twelve samples taken from these sections have been examined in an attempt to determine the geochemical...
Abstract In this research, the corrosion behavior of the copper and copper alloy in different conditions and environment were studied. The corrosion behaviour and mechanism for copper and copper alloy in( HNO3, H2SO4,HCl, NaCl)solutions were studied by chemical mass loss, kinetic of corrosion, half life time, inhibitor efficiency and corrosion rate of inhibitor efficiency methods at25oC.were also investigated. The chemical results revealed that copper and copper alloy corrodes in( HNO3, H...
ABSTRACT Malaria is a deadly disease killing millions of people every year. Different countries of the world, governmental and non-governmental organizations including World Health Organization have taken it as a challenge to address the issue of deaths associated with malaria. Prompt and accurate diagnosis is a major key in medical field. This prompts for the need to develop a Bayesian base approach to malaria fever diagnosis. A machine learning technique Bayesian was used on labelled sets ...
ABSTRACT This study was undertaken to determine the natural raaionuclides activities of 238U, 232Th, and 4°K as contaminants and their distribution from dust particles obtained from selected qua1Ties in Ekiti and Ondo States. This work was performed in four quarries sites located in Ekiti and Ondo States and a control sample. The radioactivity concentrations of the natural radionuclides (238U. 232Th and 4°K) in the collected quarries dust samples were determined by gamma ray spectrometry. ...
ABSTRACT Unique properties of silver (Ag) and its allied nanoparticles are of great interest in the fields of chemistry and technology. However, the widespread applications of nanoparticles call for synthesis routes involving eco-friendly procedures. Silver nanoparticles (Ag NPs) and their hybrids nanoparticles (Ag-Ni and Ag-Co) were synthesized using locally available biodiversity plants as alternative method to the expensive and toxic chemicals previously used. Fresh plants were collected ...
ABSTRACT The study examined men's involvement in prevention of mother-to-child transmission (PMTCT) ofl-IIV programmes in the Federal Teaching Hospital Ido-Ekiti, Ekiti State, Nigeria. The study aimed at identifying correlates of PMTCT in the hospital. Questionnaires was used to elicit information from eligible respondents in the study area. Response were analysed at univariate by using simple frequency distribution and percentage. Cross- tabulation was done to examine the relationship betwe...
ABSTRACT The study described the neighborhood factors influencing contraceptive use among adolescents in Ile Ife. The problems of unwanted pregnancy and inadequate use of contraceptive methods among adolescents is worse in developing countries like Nigeria due to uneven distribution of contraceptives and lack of knowledge on its uses. This study was carried to examine the neighborhood factors affecting contraceptive knowledge among adolescents in Ile Ife. The study made use of primary data wh...
Abstract Nigeria is a country with one of the world’s highest rate of under-five mortality. Any innovative research aimed at bringing solutions to this problem should be considered worthwhile. This study examined how socio-economic, demographic and cultural factors (called underlying factors), influence under-five mortality in Nigeria by identifying some other direct factors (called proximate determinants) through which the underlying factors influence under-five mortality. It used data fro...
Abstract Nigeria is a country with one of the world’s highest rate of under-five mortality. Any innovative research aimed at bringing solutions to this problem should be considered worthwhile. This study examined how socio-economic, demographic and cultural factors (called underlying factors), influence under-five mortality in Nigeria by identifying some other direct factors (called proximate determinants) through which the underlying factors influence under-five mortality. It used d...
ABSTRACT Games of strategy, such as chess have served as a convenient test of skills at devising efficient search algorithms, formalizing knowledge, and bringing the power of computation to bear on “intractable” problems. Generally, minimax search has been the fundamental concept of obtaining solution to game problems. However, there are a number of limitations associated with using minimax search in order to offer solution to Ayo game. Among these limitations are: (i.) improper de...