Abstract Background Several human-produced volatiles have been reported to mediate the host-seeking process under laboratory conditions, yet no effective lure or repellent has been developed for field application. Previously, we found a gradation of the attractiveness of foot odors of different malaria free individuals to Anopheles gambiae sensu stricto Giles. In this study, foot odor of the individual with the most attractive ‘smelly’ feet to the An. gambiae was collected, analyzed and ...
Abstract Bacteremia is a leading cause of death in sub-Saharan Africa where childhood mortality rates are the highest in the world. The early diagnosis of bacteremia and initiation of treatment saves lives, especially in high-disease burden areas. However, diagnosing bacteremia is challenging for clinicians, especially in children presenting with co-infections such as malaria and HIV. There is an urgent need for a rapid method for detecting bacteremia in pediatric patients with co-morbiditie...
Abstract We report here the genome sequence of a Staphylococcus xylosus clinical isolate, strain SMA0341-04 (UGA5), which contains one chromosome and at least one plasmid. Notably, strain SMA0341-04 (UGA5) contains the tetracycline efflux major facilitator superfamily (MFS) transporter (tetK) gene.
Abstract Here, we report the genome sequences of a Staphylococcus aureus clinical isolate, strain SMA0034-04 (UGA22), which contains one chromosome and one plasmid. We also reveal that isolate SMA0034-04 (UGA22) contains loci in the genome that encode multiple exotoxins.
Abstract Here, we report the sequence of a Staphylococcus pettenkoferi clinical isolate, strain SMA0010-04 (UGA20), which contains the PC1 beta-lactamase (blaZ) gene.
Abstract Background Sulfadoxine-pyrimethamine (SP) is the only anti-malarial drug formulation approved for intermittent preventive treatment in pregnancy (IPTp). However, mutations in the Plasmodium falciparum dhfr (Pfdhfr) and dhps (Pfdhps) genes confer resistance to pyrimethamine and sulfadoxine, respectively. Here, the frequencies of SP resistance-associated mutations from 2005 to 2018 were compared in samples from Kenyan children with malaria residing in a holoendemic transmission region...
Abstract ABSTRACT: Radicalization is the process by which people come to adopt in- creasingly extreme political, social or religious ideologies. When radicalization leads to violence, radical thinking becomes a threat to national and international security. Prevention programs are part of an effort to combat violent extremism and terrorism. This type of initiative seek to prevent radicalization process from occurring and tak- ing hold in the first place. In this paper we introduce a simple c...
Abstract Background: With the increasing world population, there is increasing demand for food. This has led to overuse of agricultural farms causing reduced soil fertility and accumulation of phytopathogens. Inorganic fertilizers and pesticides have been extensively used in response to these challenges. Extensive integration of inorganic fertilizers and pesticides in the farming system has contributed to soil and water pollution worsening the eutrophication in rivers lake waters. Alternativ...
Abstract Fish products may be important vectors of human exposure to heavy metals. However the understanding of how heavy metals bioconcentrate in different fish species (sp.) through contaminated environments such as wastewater treatment lagoons is very limited. In this study bioconcentration and Interspecies Uptake of Heavy Metals by three fish species (Oreochromis niloticus, Clarius gariespinus and Protopterus aethiopicus) receiving naturally contaminated wastewater was investigated. Tiss...
Abstract Aims: To evaluate the stability of Salvianolic acid A (SAA), a promising cardiovascular drug candidate. Additionally avail an archetype in-vitro therapeutic monitoring from SAA degradation profile for characteristic oral gavages. Study Design: Experimental by laboratory analysis. Place and Duration of Study: Department of Chemistry & Biochemistry, Moi University; Department of Pure & Applied Chemistry and Department of Medical Laboratory Sciences of Masinde Muliro University of Scie...
Abstract Aim: To screen the Kenyan Ganoderma lucidum for phytochemicals and to investigate it's potential in the management of some disease-causing microbes. Study Design: Hexane, ethyl acetate and methanol extraction; phytochemical study and anti-microbial activities were analysed on Kenyan G. lucidum mushroom. Place and Duration of Study: Masinde Muliro University Science laboratories from January 2019 and March 2019. Methodology: Sequential extraction of dried samples was done using hexan...
Abstract Pd-F:SnO2 thin films have been prepared by spray pyrolysis technique. Optimization has been done by doping SnO2 with palladium at varying levels of concentration and then recording sheet resistance. The sheet resistivity has been observed to decrease gradually as at% Pd concentration is increased; an optimum sheet resistivity value of 2.71 × 10−2 Ω cm has been recorded. The decrease in sheet resistivity has been attributed to presence of Pd ions which contribute in increment of...
Abstract In this paper, we use the idealization procedure for finite rings to construct a class of quasi-3 prime Near-Rings N with a Jordan ideal J(N) and admitting a Frobenius derivation. The structural characterization of N; J(N) and commutation of N via the Frobenius derivations have been explicitly determined.
Abstract Infant mortality is an important marker of the overall society health. The 3rd goal of the Sustainable Development Goals aims at reducing infant deaths that occur due to preventable causes by 2030. Due to increased infant mortality the Kenyan government introduced Free Maternal Health Care as an intervention towards reducing infant mortality through elimination of the cost burden of accessing medical care by the mother and the infant. The study examines the impact of Free Maternal H...
Abstract Exposure to microcystin poses a potential health hazard to humans and other living organisms. This results from eutrophication and warrants an investigation into the problem of microcystin toxicity in Lake Victoria. This study was conducted in Homa Bay, Kisumu, Siaya and Busia counties to understand the effects of microcystin toxicity among fisherfolk and lake riparian communities. Data collection involved 90 semi-structured questionnaires, 11 key informant interviews and seven focu...