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Abstract The current approach of morbidity control of schistosomiasis, a helminth disease of poverty with considerable public health and socioeconomic impact, is based on preventive chemotherapy with praziquantel. There is a pressing need for new drugs against this disease whose control entirely depends on this single drug that has been widely used over the past 40 years. We argue that a broader anthelminthic approach supplementing praziquantel with new antischistosomals targeting different p...
India is treasure of traditional Knowledge which has been disseminated through non-institutional means from generation to generation and is, for the most part, undocumented. However, the knowledge about microbial world by Indian Rishis presented in Sanskrit Shlokas or Suktas of our traditional manuscripts such as Vedas remained unseen. Before the invention of microscope modern science had little knowledge about the microbial biodiversity which is very clearly Presented in Vedas and Gita. ...
Vedas are considered Ultimate Source of Knowledge and the most ancient written literature of the world. All great ancient thinkers and Philosophers. From Brahma down to Jaimini opine that the Vedas are as old as the advent of man and believe that the Vedas are Revelation. The natural outcome of the. Optimistic and robust outlook, which the ancient Indians had on life, was a keen desire to live a long and healthy life of a hundred years. They advocated the theory “Prevention is better tha...
Abstract This study investigated the microorganisms associated with the spoilage of tomato (Lycopersicum esculentum) obtained from two markets in Jahun town, Jahun Local Government in Jigawa State, Nigeria. A total of five species of bacteria were isolated and identified viz: Bacillus subtilis, B.aureus, Escherichia coli, Klebsiella aerogenes and Staphylococcus aureus. The most prevalent bacterial isolate was Bacillus subtilis with 24% and was found in all samples from the two markets. Klebsi...
ACTINOMYCETE are the most widely distributed group of micro organisms in nature which primarily inhabit the soil.(oskay)
ABSTRACT The aim of this study was to characterize avian pathogenic Escherichia coli (APEC) and extended spectrum beta-lactamase (ESBL)-producing Escherichia coli strains isolated from chicken in Enugu State, Nigeria. Dead and moribund chickens collected from twenty four farms in 6 LGAs of the state and organ samples from chicken submitted to our departmental necropsy unit were used for the study. A total of 182 samples comprising of 100 broiler and 82 layers diagnosed of colibacillosis were ...
Abstract This was analytical study conducted during the period from January to April 2017, to determine the antimicrobial activity of Azadirachta indica leaves methanolic extract against different bacteria isolated from urinary tract infection. A total of 130 urine samples were collected from patients with Urinary tract infection. These specimens were inoculated into Cystine Lactose Electrolyte Deficiency (CLED) media and incubated aerobically at 37 C for 24 hrs. The clinical isolates were th...
ABSTRACT Hepatitis B Virus (HBV) occurs worldwide with more than 2 billion people being infected at some time in their lives. Transmission of this virus from carrier mothers to babies can occur during perinatal period. This study was conducted to determine prevalence of HBV infection among pregnant women in Rea Sea State. The study was carried out during the period from April to July 2017. A total of ninety one (n=91) pregnant women were enrolled in this study. Sociodemographic data including...
Abstract Introduction: One of the most serious issues in medicine is increasing resistance of Gram negative bacilli to antimicrobial agents especially broad spectrum antibiotics such as carbapenems and colistins. This fact is associated with higher mortality and morbidity rates, prolonged hospital stays and increased treatment related costs.Medicinal plants appeared to be the best alternative source for new antimicrobial drugs.. Nigella sativa is an herbaceous plant whose seeds have beenused ...
Introduction: Prevalence of resistant microbial strains is increasing with time; due to the extensive and indiscriminate use of the broad spectrum antimicrobial drugs that render the current used antimicrobial agents insufficient to control some microbial infections. Objective: The present study was aimed to investigate the antimicrobial and antioxidant potential of methanolic extract of the medicinal plant Hibiscus sabdariffa L. Method: The agar well diffusion technique was used to determin...
ABSTRACT Bacteremia is one of the most significant public health concerns and is a challenge in critical care of a patient. Early diagnosis of bacteremia could be vital step in estimating appropriate treatment as well as beginning of it. The current study aims to discover the pervasiveness of different bacterial species responsible for causing bacteremia around the population of various gender and age group and enabling the doctors for choosing the verifiable antimicrobials through...
ABSTRACT Normal vaginal flora contains a wide range of microorganisms. Bacterial vaginosis BV is the main reason for vaginal discharge. Many gram-positive and gram-negative rods i.e. E.coli, Klebsiella, Proteus, Acinetobacter and Pseudomonas spp. are major contributors to bacterial vaginosis. Aim: The present study was conducted to elucidate the frequency of various bacteria in high vaginal swabs and the sensitivity pattern of bacteria to antibiotics that are currently used Material and Metho...
ABSTRACT Extended-spectrum beta-lactamases (ESBL) are enzymes that confer resistance to most beta-lactam antibiotics, including penicillin, cephalosporin, and the aztreonams. The aim of this present study is to phenotypically identify and establish the presence of ESBL-producing organism among students in the university community. Within the University community of Godfrey Okoye University, Enugu, early morning urine samples of midstream-catch were collected into sterile bottles from sixty (6...
ABSTRACT This research was conducted in Microbiology Laboratory of Godfrey Okoye University to determine the antimicrobial efficacy of aqueous, methanol, ethanol of Pisdium guajava and Citrus x sinensis on the pathogenic Streptococcus mutans and Candida albicans. The Dimethyl sulfoxide was used for dissolving the plant extracts. Pisdium guajava showed antimicrobial activity against C. albicans with the exception of methanol showing no zone of inhibition to any of the isolates. The aqueous...