This new microfluidic platform offers a more sensitive method for screening drugs and their effects on the locomotion of free living and parasitic nematodes. The chip is capable of monitoring four nematode parameters (number of worms responsive, number of worms leaving the drug well, average worm velocity and time until unresponsiveness) to provide a more detailed analysis and resolution of drug resistance. The drug screening experiment is divided into three parts: pre-exposure study, dose ex...
The transmembrane proteins known as ion channels play a role in controlling and preserving the ionic concentrations across the cell membrane. Modeling the flux of ions in and out of these channels on an atomic level is essential for understanding several neurological diseases and related pharmaceutical discoveries. Recent experimental research has provided information on the channel's physical structure which can be used to create realistic ion transport models. Different trajectories exist f...
The transmembrane proteins known as ion channels play a role in controlling and preserving the ionic concentrations across the cell membrane. Modeling the flux of ions in and out of these channels on an atomic level is essential for understanding several neurological diseases and related pharmaceutical discoveries. Recent experimental research has provided information on the channel's physical structure which can be used to create realistic ion transport models. Different trajectories exist f...
This paper looks at a movement-based assay to analyze adaptability in Caenorhabditis elegans locomotion behavior. A series of sinusoidal microchannels of fixed wavelength and varying amplitude, with the width being similar to the body diameter of the organism, are used for this purpose. The worms are allowed to enter the channel from the input and transition towards the output port. In sections that are similar to the worms' undulations, the movement is fast and steady. However, as the channe...
This paper looks at a movement-based assay to analyze adaptability in Caenorhabditis elegans locomotion behavior. A series of sinusoidal microchannels of fixed wavelength and varying amplitude, with the width being similar to the body diameter of the organism, are used for this purpose. The worms are allowed to enter the channel from the input and transition towards the output port. In sections that are similar to the worms' undulations, the movement is fast and steady. However, as the channe...
An open microfluidic system has been developed to dispense and manipulate individual droplets on plastic sheets. Superhydrophobic material is applied to the surface of obtainable plastic sheets by spraying, then hydrophilic symbols are printed with an inkjet printer. The plastic sheets are connected to a two-axis tilting platform driven by stepper motors, which produces mechanical agitation enabling droplet transport. The system has been demonstrated to carry out various droplet operations, s...
Emmanuel, O. (2008). Taking risky opportunities in youthful content creation: teenagers' use of social networking sites for intimacy, privacy and self-expression. New Media & Society, 10(3), 393-411
An Introduction to Computer Science and Problem Solving
INTRODUCTION TO PROBLEM SOLVING An algorithm is a sequence of simple steps that can be followed to solve a problem. These steps must be organized in a logical, and clear manner. We design algorithms using three basic methods of control: sequence, selection, and repetition. 1.1 Sequential control. Sequential Control means that the steps of an algorithm are carried out in a sequential manner where each step is executed exactly once. Let’s look at the following problem: We need to obtain the t...
A computer is an electronic device that receives input, stores or processes the input as per user instructions and provides output in desired format. Input-Process-Output Model Computer input is called data and the output obtained after processing it, based on user’s instructions is called information.
What is Computer Science? 6 • Computer Science can be summarized with two simple words: problem solving. • Computer Science is the study of problems, problem-solving, and the solutions that come out of this problem-solving process. • Given a problem, the goal is to develop an algorithm to solve the problem. • An algorithm is a step-by-step list of instructions to solve the problem.
Course Requirements, Grading, & ASSESSMENT: Students will earn a passing grade upon successful completion of the following 1. Weekly lectures 5 points. To earn full points for this learning activity you need to attend weekly classes 2. Weekly readings and summary of the readings 5 points. Submission deadline for this learning activity is every Monday by 06:00am 3. Weekly reflective journal entry 7 points. Submission deadline for this learning activity is every Sunday by 10:000pm 4. Weekly dis...
This study aimed at identifying the Challenges faced by Pastoralists in East Africa, the importance of pastoralism to the economy and people's livelihoods and the recommendations to help solve the problems
ABSTRACT The study examined the impact of prior exposure to Laboratory apparatus on acquisition of science process skills, academic achievement and retention in chemistry among secondary school students in Giwa Educational Zone. A total of 120 Senior Secondary two (SS II) chemistry students were in the study from a total population of 996. Non randomized pretest, post posttest, posttest experimental - control groups research design was used for the study. Chemistry Achievement Test (CAT) and...
Abstract Single stage alkali-catalyzed transesterification of vegetable oils having free fatty acid(FFA) content above 0.5% promotes saponification which lowers the biodiesel yield bydeactivating the catalyst. A strong solid base KF/Eggshell catalyst, which is capable ofcircumventing saponification while producing biodiesel in a single stage from neem oilhaving FFA content of 4.2% was synthesized. The catalyst was synthesized by a thermaltreatment of chicken eggshell at 900oC, followed by ...