ABSTRACT We report what, as far as we are aware, is the first documented case of Alagille syndrome which is characterized by chronic cholestasis. characteristic facies, pulmonary stenosis and defects at' the vertebral arch, in a Nigerian girl who presented at the age of two days and was followed up intermittently for a period or 10.5 years.
ABSTRACT The clinical and public health implications of the convergence of Human Immunodeficiency Virus (HIV) epidemic and chronic viral hepatitis in Sub-Saharan Africa are poorly understood.
ABSTRACT Various target groups have been identified in Nigeria for studying the prevalence of hepatitis B virus infection;
ABSTRACT There is dearth of information on Hepatitis E virus (HEV) infection and its co-infection with HBV among Nigerian healthcare workers.
ABSTRACT We surveyed a random sample (n=75) of doctors and dentists at University College Hospital, Ibadan, Nigeria.
ABSTRACT Over the period 1st October 1999 to 30th April 2002 a clinical trail of the modified short course chemotherapy in newly diagnosed cases of pulmonary tuberculosis with human immunodeficiency virus (HIV) infection in Ibadan, Nigeria was carried out.
ABSTRACT Background: Variable fetal biometric values are common in normal fetuses and it is natural to assume that ethnicity might influence this. There is the potential danger of misinterpretation of such observed normal variations. Aims: The study aim was to determine whether differences in ultrasound-measured fetal biometry exist among pregnant women of the Akan, Mole-Dagbon, Ewe and Ga-Adangbe ethnic groups in Accra. Methods: This was a prospective cross-sectional study involving 448 wome...
ABSTRACT A prospective cohort study of infants admitted to the special care baby unit University College hospital Ibadan has revealed a 24.5 percent prevalence of patency of the ductus arteriousus among 97 infants who where admitted over a six month period.
ABSTRACT A qualitative, community-based study was conducted in the rural community of Ago Are in southwestern Nigeria to learn about indigenous surgical practices and their potential for disease transmission. Community leaders as key informants assisted in identifying two types of indigenous practitioner whose work involved blood contact, whose work was observed. The ol6lil are surgeons who specialize in circumcision and making traditional facial-markings, while the generic term for healer, o...
ABSTRACT Objective: Hepatitis B virus infection is common in Nigerians and its diagnosis is necessary for effective treatment and eradication. This study is aimed at highlighting the serological factors jeopardizing the diagnosis and treatment of the infection among Nigerians adults.
ABSTRACT Hepatocellular carcinoma (HCC) is usually diagnosed at an advanced stage, when little remedy could be offered. There is a need for relatively affordable, available and noninvasive tests for diagnosis, staging and detection of metastasis among individuals at risk. A clinical, chest radiographic (CXR) and abdominal ultrasonographic examination was carried out to detect and evaluate the pattern of metastasis among 53 untreated patients. One patient had clinical paraparesis with no outwa...
ABSTRACT A prospective study aimed at determining the relationship between hepatitis C virus (HCV) infection and serum ferritin in Nigerian patients with primary liver cell carcinoma (PLCC) was carried out at the University College Hospital (UCH), Ibadan; Nigeria. The study involved 42 adult Nigerians made up of 14 healthy subjects as controls and 14 patients each with PLCC and liver cirrhosis (LC) who consented to participate in the study. The subjects were controlled for age and sex. The di...
ABSTRACT Ocular complications occurred in 2g°Ic, or children with head injury. Neuro-ophthalmological lesions made up one-third or these complications, mostly involved the optic nerve, and were associated with other focal neurological signs more Frequently than non-neural ocular complications. Lesions or the posterior visual pathways were rare but tended to be permanent.
ABSTRACT Traumatic disruption of the posterior urethra usually occurs in association with pelvic fractures and may result in significant morbidity. The management of this injury remains difficult and controversial. Recently, early restoration of urethral continuity in these patients using either both antegrade and retrograde cystoscopy (with or without fluoroscopy), or flexible retrograde urethroscopy alone under general aneasthesia, has been reported with good results.
ABSTRACT Peyronie's disease is characterized by the formation of fibrous plaques within the tunica albuginea of the corpora cavernosa. It is a frustrating disease to the patient resulting in penile deformity and painful erection and erectile dysfunction. There is mixed response to medical therapy and the numerous surgical options implies no standardized procedure yet. The incidence appears to be increasing but this disease is rarely reported in Nigeria. We present three cases of dorsal and ve...