ABSTRACT In the first part of this thesis, a brief survey of the chemistry of veratramine viz. its occurrence, isolation and structural diagnosis is given. This part also includes a review of recent work on the stereochemistry and the synthetic work of other workers on the alkaloid. The main section describes three approaches to the synthesis of the C-Nor-D-homo ring system of the veratrura alkaloids. Howell and Taylor’s acétate diester 6(3-acetoxy-1 p:2adi (methoxy carbonyl methyl)-9P~me...
ABSTRACT In this dissertation, Markov chain was used to model the rainfall pattern and sunshine duration for three regional capitals in Ghana (Tamale, Kumasi and Accra). Data on mean monthly averages and daily figures of measured parameters (sunshine duration and rainfall) for five years were used. To achieve these goals, a statistical basis was presented before adopting the three main approaches for modeling. Transition Matrix shows the short-run behavior of Markov chain; the steady-state pr...
Malaria merozoite surface protein 1 (MSP1) is cleaved in an essential step during erythrocyte invasion. The responses of children to natural malaria infection included antibodies that inhibit this cleavage and others that block the binding of these inhibitory antibodies. There was no correlation between the titer of the antibody to the 19-kDa fragment of MSP1 and its inhibitory activity. These findings have implications for the design of MSP1-based vaccines.
ABSTRACT The purpose of this study was to investigate the perceptions of teachers and students towards the use of mobile technology in the teaching and learning process. Also the study sought to recommend a model for teaching and learning using mobile technology tools. The descriptive research was used for the study. In all, 375 respondents participated in the study. They were made up of 300 students and 75 teachers selected from senior high schools in the Cape Coast Metropolis. Structured qu...
ABSTRACT The study seeks to determine the availability and utilization of ICT facilities for teaching in selected basic schools within Cape Coast North constituency in the Central Region of Ghana. The objective of the study is to compare the availability of ICT facilities in Cape Coast North constituency and ascertain the teachers’ level of knowledge regarding the utilization of Information and Communication Technology (ICT), and how ready and willing teachers are to use ICTs facilities ava...
ABSTRACT Radiation dose to bladder and rectum in the treatment of cervical cancer using high dose rate brachytherapy is a limiting factor to the delivery of the prescribed dose to the target. The objective of this study is to determine absorbed dose to the bladder and rectum (organs at risk) in the treatment of cervical cancer using multisource high dose rate brachytherapy treatment system in order to establish an in-vivo dosimetric and quality assurance protocol for patient treatment. A phan...
ABSTRACT In this study, the International Center for Theoretical Physics’ Region l Climate Model Version 4 (RegCM4) is used over the period 1998-2010, to study the dynamics of rainfall over West Africa. The study also attempts to understand the West African Monsoon (WAM) circulation and its characteristics. Global Precipitation Climatology Project precipitation (GPCP), Tropical Rainfa ll Measuring Mission (TRMM), global atmospheric reanalysis (ERA-Interim, ERAINT), RegCM4 winds and National...
ABSTRACT This research was conducted to detennine the levels of mercury, cadmium and zinc in the leaves of Xanthosoma sagittifoliwn (kotombre), Marlihot esclIlenta (cassava leaves) and the conn of Colecasia esclIlenta (taro conn) growing in the mining communities of Tarkwa, Prestea, Bankyim and Agona Junction. The Random sampling method was used to collect the samples and the wet digestion method was used to digest the samples for AAS analysis. A statistical analysis of the results of the res...
Abstract Malaria remains a major parasitic disease in Africa, with 300–500 million new infections each year. There is therefore an urgent need for the development of new effective measures, including vaccines. Plasmodium falciparum merozoite surface protein-119 (MSP-119) is a prime candidate for a blood-stage malaria vaccine. Blood samples were collected from children aged 10 days to 15 years in the months of January–March (N = 351) and October–November (N = 369) corresponding to the d...
ABSTRACT This study investigated the effect of the use of computers on students’ learning of Trigonometry in Mathematics. A class was selected in each of two randomly selected schools. The pretest-posttest non-equivalent quasi experimental design was used. The students in the experimental group learned Trigonometric concept through the Computer Based Instruction (CBI), whereas the students in the control group were taught the same concepts using the conventional approach. The conventional ...
ABSTRACT Incidence of malaria in the Central Region of Ghana was investigated to determine age group and sex vulnerability as well as the parasite species distribution, haemoglobin status of patients and herbs used in treating the disease. Four Hospitals were used as study centers namely, Cape Coast District Hospital and the University of Cape Coast Hospital constituting the coastal zone; Saint Francis Xavier Hospital at Assin Foso and Our Lady of Grace Hospital at Breman Asikuma form...
ABSTRACT Despite the effort Government and other stakeholders are making to support Ghanaian senior high schools in ICT, most of the schools are teaching ICT as an isolated subject rather than integrating the ICT resources into the educational curriculum to improve teaching and learning. The objective of the study was to assess the integration of ICT resources in teaching and learning in senior secondary schools in the Cape Coast metropolis. A total of 270 respondents took part in the survey...
ABSTRACT The purpose of this study was to examine the outcome on the use of digital technologies to teachers and pupils in Junior High Schools in Ahafo Ano South East district and Nhyiaeso sub-metropolitan areas in the Ashanti Region of Ghana and also to integrate Computer Assisted Instruction (CAI) that will facilitate teaching and learning in the classroom. Both quantitative and qualitative research methodology were used. Simple Random sampling technique was used to sample 258 pupils and te...
ABSTRACT The use of sulfadoxinepyrimethaine (SP) as an intermittent preventive treatment (IPT) against malaria during pregnancy has become a policy in most sub-Sahara African countries but crucially depends on the efficacy of SP. This study sets out to evaluate the effectiveness of the SP given to the pregnant women in the selected health facilities in the Central region of Ghana to prevent maternal malaria in the pregnant women. A cross-sectional study was carried out to evaluate the effecti...
ABSTRACT Open sun drying (OSD) has been a fish processing method for ages. In Ghana women form a large number of processors. Post-harvest losses still prevail in the trade due to poor fish handling, processing and storage which results in poor quality of dried fish. Solar drying has been introduced to improve on quality of OSD dried fish. A survey of open sun drying practices (OSD) at Kasoa (Central Region) and Tema (Greater Accra Region) showed poor hygiene practices and low value of product...