Biochemistry Research Papers/Topics

Prophylactic Efficacy of Aqueous Extract of Curcuma longa against Indomethacin-Induced Ulcer in Male Wistar Rats

Evaluation of the anti-ulcerogenic andprophylactic efficacy of aqueous extract ofCurcuma longa on indomethacin-induced ulcer inalbino rats was the aim of this study. Thirty adultmale rats of body weight between 150 and 200gwere used and were divided into six groups of fiverats each. Group I was treated with 0.8mg/ml ofOmeprazole for seven days. Group II was treatedwith a solution of 0.8 g/ml Curcuma longa forseven days, while group III received distilled waterfor seven days. This group served...

Toxicological assessment of the methanolic leaf extract of Bridelia ferrugelia

This study evaluated the acute and subacute toxicity effects of Bridelia ferrugelia leaf extract. Observation of the acute group showed that LD50 of the extract is greater than 2000 mg/kg. The subacute investigation was determined by administering 200 mg/kg, 400 mg/kg and 600 mg/kg of the methanolic leaf extract to male Wistar rats for 28 days with distilled water as a control. Haematological and biochemical parameters, as well as lipid levels of vital organs, were examined. Toxicological eva...

Review on Application of Enzymes in fruit juice processing

Enzymes are organic catalyst that alters the rate of biological reactions. The application of enzymes to industries has been one of the emerging prospects in the science world in other to optimize production. This paper aims to give an overview of the possible application of different enzymes to fruit juice production to enhance yield and minimize cost.  

Review on the Application of Biotechnology in Garri production in Nigeria

Biotechnology presents a promising potential for food biosecurity, healthcare, and bioremediation. Gari is a widely consumed staple diet in Nigeria and it is imperative to study how its quantity and nutritional value can be enhanced using biotechnologies. This paper provides a short but concise overview of the possible applications of biotechnological techniques to enhance the productivity of Nigerian most consumed staple diet- Gari for the sustenance of her economy.

BIOFERTILIZER: A KEY TO SUSTAINABLE AGRICULTURE

ABSTRACT Current soil management strategies are mainly dependent on inorganic chemical-based fertilizers, which caused a serious threat to human health and environment. The exploitation of beneficial microbes as a biofertilizer has become paramount importance in agriculture sector for their potential role in food safety and sustainable crop production. The eco-friendly approaches inspire a wide range of application of plant growth promoting rhizobacteria (PGPRs), endo- and ectomycorrhizal f...

ANTIBIOTIC SUSCEPTIBILITY OF Staphylococcus aureus IN CATTLE

ABSTRACT        This work was done to determine the antibiotic susceptibility of Staphylococcus aureus among cattle in Owerri, Imo State. A total of twenty four (24) samples were collected which were cultured on appropriate bacteriological media. The Staphylococcus aureus isolates were identified by standard biochemical tests. Antibiotic susceptibility profile of the isolates was performed according to Clinical and Laboratory Standard Institute (CLSI) guidelines. Out of the 24 sample...

The nutritional and chemical constituents of different extracts of Neem leaf (Azdirachta indica) and their effect on the haematology and histopathology of Wistar Albino Rats

                                                       ABSTRACT                                   The nutritional and chemical constituents of different extracts of Neem leaf (Azdirachta indica) and their effect on the haematology and histopathology of Wistar Albino Rats were investigated. The samples analyzed includes processed and unprocessed leaves extract of Neem plant using cold water, hot water, 40% ethanol, 30%  methanol,...

Assessment of some micronutrient in sesamum indicum

ABSTRACT Sesamun indicum is used for both domestic and commercial purpose in Northern Nigeria, this research is aimed at assessing some micronutrients in sesamum indicum seed in Nguru town, using atomic absorption spectroscopy, spectrophotometric and flame photometric techniques in order to determine the elemental concentrations of  some elements in sesame seeds collected from Nguru town, Nguru local government of Yobe state, Nigeria. The results showed the presence of sodium (Na), potassium...

In-vitro Modification of Acetylcholinesterase activity in adult head of Zonocerus variegatus: a biomarker to effects of most chemical agents.

ABSTRACT Acetylcholinesterase(AChE) is the key cholinesterase in the body which catalyzes the breakdown of acetylcholine and some other choline esters that functions as neurotransmitter in living cell. It belongs to the carboxyl esterase (hydrolase) family of enzymes which are found mainly at the neuromuscular junction (point of contact between the nervous system and the muscles) and the chemical synapses of the cholinergic types. It functions to terminate synaptic transmission by breaking d...

The organ distribution and characterization of Acetylcholinesterase in Adult African Grasshopper: Zonocerus variegatus and Zonocerus elegans.

Acetylcholinesterase (AChE) is the primary cholinesterase in the body which catalyzes the breakdown of acetylcholine and some other choline esters that functions as neurotransmitter in living cell. It belongs to the carboxyl esterase (hydrolase) family of enzymes which are found mainly at the neuromuscular junction (point of contact between the central nervous system and the muscles) and the chemical synapses of the cholinergic types. It functions to terminate synaptic transmission by breakin...

Student industrial work experience report at Nigerian Bottling Company, Asejire

 ABSTRACT The students industrial work experience scheme (SIWES) is a skill impacting program designed to expose and prepare students of universities and other tertiary institutions for the industrial work situation that may be encountered after school. My SIWES program was undertaken at Nigeria Bottling Company limited, Asejire plant, Ibadan; a company that deals with the manufacturing of non-alcoholic beverage products such as Coca-Cola, limca, Fanta orange etc. The company has various se...

Inhibition of mitochondria pyruvate carrier- an approach to attenuating neurodegeneration

ABSTRACT Neurodegeneration is defined as the progressive loss of structure or function of neurons in the body. Different forms of neurodegenerative disease include Parkinson disease, Alzheimer disease, multiple sclerosis, Huntington’s disease, and they are caused by different mechanism such as inflammation, mitochondria dysfunction, excitotoxicity etc. Insulin sensitizers have been discovered by researchers in managing Neurodegeneration and the main one used are the thiazolidinedione. Due ...

Comparative biochemical effect ofoleanolic acid and rutin on acute kidney injury in wistar rats

ABSTRACT The inability of an organism to efficiently remove excess waste from the body have been a major issues attached to acute kidney injury (AKI) which is the most common cause of organ dysfunction. Oleanolic acid and rutin which are from the families of saponin and flavonoid respectively have been discovered to possess certain biological activities such as anti-oxidant, anti-inflammation, anti-viral and nephroprotective activities that can help in therapeutic management of acute kidney ...

A review on the Pathogenesis of Diabetes mellitus

The article gives a brief overview of what Diabetes mellitus is, its type and pathogenesis. It's aimed at enlightening people about this disorder. 


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