Biochemistry Research Papers/Topics

Toxicological Effect of Monosodium Glutamate in Seasoning on Human Health

The use of seasonings to enhance the flavor of food has been on the increase in recent time. Different types of seasonings are produced daily. Theconstituent of these flavor-enhancers is unknown to ignorant consumers. They only want to eat food with good taste without consideration of theeffect of these additives on their health. These seasonings contain monosodium glutamate (MSG) which really spiced the food. This review focuses onthe toxicological effect of monosodium glutamate in seasoning...

Quality Assessment of Sachet and Bottled Water in Ogbomoso Metropolis, Nigeria

Background: Access to potable water has become a difficult task in many countries of the worldincluding Nigeria. In Nigeria, the government is trying her best to make water supply available tothe masses but till now this vision has never been accomplished. If those living in urban areascould not have access to portable water supply by the government, what is the fate of the peopleliving in rural areas? This has led to increased usage of sachet and bottled water as portabledrinking water.Aim: ...

Assessment of Sachet and Bottled Water Quality in Ibadan, Nigeria

Background: With the recent increase in the consumption of sachet and bottled water in major cities and towns of Nigeria due to lack of portable drinking water, there is need to investigate the prevalence of possible contaminants in these water that may have toxicological effect on human when consumed.Aim: Quality assessment of sachet and bottled water produced and/or sold in Ibadan, Nigeria was the aim of this study.Place and Duration of Study: This research was carried out in Ibadan, the Oy...

PLANT SECONDARY METABOLITES: EFFECTS ON REDUCTION OF METHANE AND CARBONDIOXIDE FROM LIVESTOCK PRODUCTION

Table of Contents   Certification. ii DEDICATION.. iii ACKNOWLEDGEMENT. iv Abstract. vi CHAPTER ONE. 1 1.0         INTRODUCTION.. 1 CHAPTER TWO.. 3 2.0         Greenhouse gases. 3 2.1         Contribution of ruminants to greenhouse gas.4 CHAPTER THREE. 5 2.0         PLANT SECONDARY METABOLITES. 5 3.1         Saponin. 6 3.2         TANNINS. 10 3.3         ESSENTIAL OILS. 13 3.4         ORGANOSULPHUR COMPOUNDS. 17 3.5     �...

The Genetics of ABC Transporter

THE GENETICS OF ABC TRANSPORTER1.0 INTRODUCTIONThe transport of organic and inorganic molecules across cellular membranes is vital to allforms of life, as it allows cells to maintain an off equilibrium condition. In Escherichia coli,for   example,   ~10%   of   the  entire   genome   is   dedicated   to   membrane-bound   and   solubleproteins involved in transport processes (Blattner et al., 1997). On the timescale relevant forcellular metabolism, the lipid bilayer rep...

Evaluation of Phytochemical Content and Antioxidant Potential of Ocimum gratissimum and Telfairia occidentalis Leaves

Aim: The aim of this study is to compare the phytochemical content and antioxidant potential of Ocimum gratissimum and Telfairia occidentalis leaves.Study Design: This study was made to fit a one-way Analysis of Variance.Place and Duration of Study: This research was carried out in the Department of Premedical Science, Educational Advancement Centre, Ibadan and Pharmaceutical Laboratory of the University of Ibadan, Nigeria between January and June, 2018.Methods: Both plants were purchased fr...

Evaluation of Moringa oleifera Leaf Potential in the Prevention of Peptic Ulcer in Wistar Rats

This study is aimed at investigating the potential ofaqueous extract of Moringa oleifera leaf in theprevention of indomethacin-induced ulcer. Toachieve this, thirty adult male rats of body weightbetween 150 and 200g were divided into six groupsof five rats each. Group I was treated with 0.8mg/mlof Omeprazole for seven days. Group II was treatedwith a solution of 0.8 g/ml Moringa oleifera leaf forseven days, while group III received distilled waterfor seven days. This group served as the contr...

Comparative Assessment of Phytochemical Content and Antioxidant Potential of Azadirachta indica and Parquetina nigrescens Leaves

Aim: The aim of this study is to compare the phytochemical content and antioxidant potential of Azadirachta indica and Parquetina nigrescens leaves.Study Design: This study was made to fit a one way Analysis of Variance.Place and Duration of Study: This research was carried out in Premedical Science Department, Educational Advancement Centre, Ibadan and Pharmaceutical Laboratory of the University of Ibadan, Nigeria between January and June, 2018.Methodology: Both plants were harvested from t...

Biochemical Mechanisms Involved in the Regulation of Appetite and Weight

The overwhelming increase in the prevalence ofoverweight and obesity in recent years represents oneof the greatest threats to the health of the developedworld and part of the developing world. Amongcurrent treatments, gastrointestinal (GI) surgeryremains the only approach capable of achievingsignificant weight loss results with long-termsustainability. As the obesity prevalence approachesepidemic proportions, the necessity to unravel themechanisms regulating appetite and weight gainhave garne...

Assessment of Bread in Ogbomoso Metropolis for the Presence of Potassium Bromate

Aim: This study is aimed at evaluating the level of potassium bromate in bread in Ogbomoso metropolis.Study Design: This study was made to fit a one way Analysis of Variance (ANOVA).Place and duration of Study: The bread samples were purchased in Ogbomoso metropolis and analyzed in Ibadan, both in Oyo State, Nigeria between July and December, 2018.Methodology: Twenty five loaves of different brands of bread were purchased in Ogbomoso metropolis and transported to Ibadan for analysis. They wer...

Evaluation of Potassium Bromate in Bread in Ibadan Metropolis Fifteen Years after Ban in Nigeria

Background: In 2003, the National Agency for Food, Drug Administration and Control (NAFDAC),the agency responsible for regulating drugs, foods and chemicals in Nigeria, banned the use ofpotassium bromate in bread on account of its deleterious effect and carcinogenicity in humans.Aim: This study is aimed at investigating the level of compliance to the use of potassium bromatein bread fifteen years after ban.Study Design: This study was made to fit a one way Analysis of Variance.Place and Durat...

Implication of Sugar Intake in Haemorrhoid and Menstruation

This review discusses the implication of sugar intake in haemorrhoid and menstruation.Haemorrhoid is the clustering of veins in the rectum leading to swollen anus. This occurs due topressure exerted on the rectum. When these veins swell, they expand outward into themembranes around the rectal and anal tissue. Most people believed that sugar is the onset ofhaemorrhoid. Haemorrhoid occurs as a result of pressure exerted on the rectum leading to theswelling of the veins in the rectum. Since suga...

Investigation of Aqueous Extract of Zingiber officinale Root Potential in the Prevention of Peptic Ulcer in Albino Rats

This study is aimed at investigating the anti-ulcerogenicand prophylactic efficacy of aqueous extract of Zingiberofficinaleon indomethacin-induced ulcer. To achieve this, thirty adultmale rats of body weight between 150 and 200g were used andwere divided into six groups of five rats each. Group I wastreated with 0.8mg/ml of Omeprazole for seven days. Group IIwas treated with a solution of 0.8 g/ml Zingiberofficinale forseven days, while group III received distilled water for sevendays. This g...

Levofloxacin induced dyslipidemia in male albino rats -

Objective: Materials and This study was aimed to investigate . whether levofloxacin perturb lipid metabolismmethods: 7.14 mg/kg body weight) of levofloxacin was administered intraperitoneally 12 hourly to Therapeutic dose (rats for 5 and 10 days. Twenty-four hours after the last levofloxacin treatment and 7 days after levofloxacin withdrawal(for a group of rats), blood and other tissues (liver, kidney, brain, heart, lung and spleen) were removed from the animalsafter an overnight fast and ana...

Mechanisms for Controlling the Synthesis of Lipids

Lipids are synthesized, transported, and recognizedby the concerted actions of numerous enzymes,binding proteins, and receptors. A comprehensiveanalysis of lipid molecules, “lipidomics,” in thecontext of genomics and proteomics is crucial tounderstanding cellular physiology and pathology;consequently, lipid biochemistry has become a majorresearch target of the postgenomic revolution andsystems biochemistry. This review is aimed atstudying the mechanisms involved in the regulation oflipids...


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